Fiber optic device for sensing analytes

Fiber optic device for sensing analytes

  • CN 1,902,476 B
  • Filed: 11/12/2004
  • Issued: 12/04/2013
  • Est. Priority Date: 11/26/2003
  • Status: Active Grant
First Claim
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1. the device for detection of glucose in sample comprises:

  • (a) the light path pipeline of near-end and far-end is arranged;

    (b) in the optical system of light path pipeline near-end, comprising;

    at least one electromagnetic energy transmitter and at least one electromagnetic energy detecting device;

    With(c) be attached to the far-end of optical fiber and the detecting element be connected with fiber optics, this detecting element comprises;

    at least one Glucose-Galactose that can specifically be combined with glucose is in conjunction with albumen, with the environment sensitive fluorophor relevant in conjunction with albumen to described Glucose-Galactose, wherein said detecting element is captured in described polymeric matrix or is attached to described polymeric matrix, and described polymeric matrix covalently and directly by the reactive group on described polymeric matrix, be attached to the described far-end of optical fiber, wherein said matrix allows described Glucose-Galactose to keep the conformation movability in conjunction with albumen, and wherein said light path pipeline transmits the variations in light of the sensitive fluorophor of described environment during in conjunction with the particular combination of albumen and glucose at described Glucose-Galactose.

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