Polymer coating for medical devices

Polymer coating for medical devices

  • CN 1,911,460 A
  • Filed: 02/14/2003
  • Published: 02/14/2007
  • Est. Priority Date: 02/15/2002
  • Status: Active Application
First Claim
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1. coating that is used for medical apparatus, it has body fluid-contact surface and is used to contact blood or other body fluid, and described coating comprises:

  • Be covalently bonded to the silane derivative layer of the body fluid-contact surface of medical apparatus, described silane derivative layer contains hydroxyl or amido functional group;

    The lactone polymer chain, its original position open loop glycerol polymerization by internal ester monomer is grown on the described hydroxyl or amido functional group of described silane derivative, described polymerization is caused by the described hydroxyl or the amido functional group of the described silane derivative that is covalently bonded to described medical device surface, and described lactone polymer chain and described silane derivative form grafted lactone polymer layer together;

    At least one polyester polymers/bioactivator is deposited upon on the described grafted lactone polymer layer, at least the ground floor of wherein said sedimentary polyester polymers/bioactivator layer is compatible with described grafted lactone polymer stratification, so that make described sedimentary polyester polymers chain and described grafted lactone polymer chain entanglement for strong bond;

    AndAt least one polymeric layer is deposited on described sedimentary polyester polymers/bioactivator layer alternatively, forms top layer or outer shell.

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