Site-specific incorporation of redox active amino acids into proteins

Site-specific incorporation of redox active amino acids into proteins

  • CN 1,942,579 B
  • Filed: 10/13/2004
  • Issued: 06/26/2013
  • Est. Priority Date: 10/14/2003
  • Status: Active Grant
First Claim
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1. a composition that contains the quadrature aminoacyl-tRNA synthetase, wherein, the preferential aminoacylation quadrature of redox active amino acids tRNA for described quadrature aminoacyl-tRNA synthetase,Wherein, the aminoacid sequence of described quadrature aminoacyl-tRNA synthetase as shown in SEQ ID NO:

  • 1, andDescribed quadrature aminoacyl-tRNA synthetase is with being selected from the described quadrature tRNA;

    3 of the preferential aminoacylation of following redox active amino acids, 4-dihydroxyl-L-Phe, 3,4,5-trihydroxy--L-Phe and 4-nitro-phenylalanine.

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