Remedy or preventive for arthritis

Remedy or preventive for arthritis

  • CN 1,960,758 B
  • Filed: 03/31/2005
  • Issued: 10/22/2014
  • Est. Priority Date: 03/31/2004
  • Status: Active Grant
First Claim
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1. guanylate cyclase B activator is for the preparation of the application of arthritic therapeutic agent or preventive,Wherein said guanylate cyclase B activator is C type profit natriurtic peptide or derivatives thereof,Wherein said C type profit natriurtic peptide is selected from the CNP-22 of SEQ ID NO:

  • 1 and the CNP-53 of SEQ ID NO;

    2, andWherein said derivant is selected from 1 to 5 amino acid whose disappearance, the displacement having in the aminoacid sequence of SEQ ID NO;

    1 or adds and have the active guanylate cyclase B activated peptide of activation guanylate cyclase B and have 1 to 5 amino acid whose disappearance, displacement in the aminoacid sequence of SEQ ID NO;

    2 or add and have a guanylate cyclase B activated peptide that activates guanylate cyclase B activity.

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