Liposomes useful for drug delivery

Liposomes useful for drug delivery

  • CN 1,980,637 B
  • Filed: 05/02/2005
  • Issued: 02/19/2014
  • Est. Priority Date: 05/03/2004
  • Status: Active Grant
First Claim
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1. for using the compositions of antineoplaston camptothecine entity, it comprises liposome, described liposome comprises one or more lipids and is encapsulated in the antineoplaston camptothecine entity in described liposome, anion with liposomes enclose, described anion is selected from eight sulphuric acid sucrose and inositol hexaphosphateWherein said liposome is in medium and has described camptothecine entity and be encapsulated in inner space wherein, described camptothecine entity is irinotecan or the special bank of holder pool, and at least four times of the anti-tumor activity height of the entity of the free non-liposome form of the anti-tumor in vivo specific activity of liposome compositionWherein said liposome contains ammonium compounds,Described ammonium compounds is selected from dimethylammonium, dimethyl ethanol ammonium, diethyl ammonium, trimethylammonium and three second ammoniums.

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