Probe for detecting matrilinear inheritance chondriosome deafness gene A1555G and its use

Probe for detecting matrilinear inheritance chondriosome deafness gene A1555G and its use

  • CN 1,987,462 A
  • Filed: 12/26/2006
  • Published: 06/27/2007
  • Est. Priority Date: 12/26/2006
  • Status: Active Grant
First Claim
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1. real time fluorescent quantitative probe that is used to detect matrilinear inheritance chondriosome deafness gene A 1555 G, it is characterized in that:

  • 5 '"'"' end of probe is arranged in the 1543-1553bp zone shown in matrilinear inheritance chondriosome deafness gene sequence SEQ ID NO;

    5,3 '"'"' end is arranged in the 1564-1574bp zone shown in chondriogen sequence SEQ ID NO;

    5, and at 5 '"'"' end mark of this probe fragment fluorescence report group, 3 '"'"' end mark the fluorescent quenching group, and the base A of 1555bp is replaced by G, is referred to as saltant real time fluorescent quantitative probe.

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