Systems and methods for stimulation-related volume analysis, creation, and sharing with integrated surgical planning and stimulation programming
First Claim
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1. A method, comprising:
- obtaining atlas registration information regarding a patient and obtaining a surgical trajectory for implantation of a leadwire;
obtaining user input of at least one desired therapeutic effect;
obtaining effects of electrical stimulations performed on a plurality of patients of a patient population;
analyzing, by a processor, the effects of electrical stimulations performed on the plurality of patients of the patient population to determine a plurality of volumes of activation (VOAs) along the surgical trajectory and utilizing the atlas registration information, wherein each of the VOAs corresponds to an estimate of a volume of tissue stimulated using a corresponding set of stimulation parameters;
scoring each of the VOAs to reflect production of the at least one desired therapeutic effect by stimulation of the VOA;
based on the analysis and scoring, determining, by the processor, a target volume and a corresponding set of stimulation parameters that are estimated to provide electrical stimulation of the target volume; and
stimulating the patient using the corresponding set of stimulation parameters for the target volume.
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Abstract
A computer implemented system and method facilitates a cycle of generation, sharing, and refinement of volumes related to stimulation of anatomical tissue, such as brain or spinal cord stimulation. Such volumes can include target stimulation volumes, side effect volumes, and volumes of estimated activation. A computer system and method also facilitates analysis of groups of volumes, including analysis of differences and/or commonalities between different groups of volumes.
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Citations
18 Claims
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1. A method, comprising:
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obtaining atlas registration information regarding a patient and obtaining a surgical trajectory for implantation of a leadwire; obtaining user input of at least one desired therapeutic effect; obtaining effects of electrical stimulations performed on a plurality of patients of a patient population; analyzing, by a processor, the effects of electrical stimulations performed on the plurality of patients of the patient population to determine a plurality of volumes of activation (VOAs) along the surgical trajectory and utilizing the atlas registration information, wherein each of the VOAs corresponds to an estimate of a volume of tissue stimulated using a corresponding set of stimulation parameters; scoring each of the VOAs to reflect production of the at least one desired therapeutic effect by stimulation of the VOA; based on the analysis and scoring, determining, by the processor, a target volume and a corresponding set of stimulation parameters that are estimated to provide electrical stimulation of the target volume; and stimulating the patient using the corresponding set of stimulation parameters for the target volume. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A system, comprising:
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at least one computer processor; and a memory coupled to the at least one computer processor and having instructions stored thereon, wherein the instructions are configured to perform the following acts when executed by the at least one computer processor; obtaining a surgical trajectory for implantation of a leadwire; obtaining user input of at least one desired therapeutic effect; obtaining effects of electrical stimulations performed on a plurality of patients of a patient population; analyzing the effects of electrical stimulations performed on the plurality of patients of the patient population to determine a plurality of volumes of activation (VOAs) along the surgical trajectory and utilizing atlas registration information, wherein each of the VOAs corresponds to an estimate of a volume of tissue stimulated using a corresponding set of stimulation parameters; scoring each of the VOAs to reflect production of the at least one desired therapeutic effect by stimulation of the VOA; based on the analysis and scoring, determining a target volume and a corresponding set of stimulation parameters that are estimated to provide electrical stimulation of the target volume; and stimulating the patient using the corresponding set of stimulation parameters for the target volume. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18)
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Specification