Expandable implant devices for filtering blood flow from atrial appendages

• US 10,278,805 B2
• Filed: 09/25/2015
• Issued: 05/07/2019
• Est. Priority Date: 08/18/2000
• Status: Expired due to Term

• Current Assignee: Atritech Inc. (Boston Scientific Corporation)
• Original Assignee: Atritech Inc. (Boston Scientific Corporation)
• Inventors: Borillo, Thomas E., Peterson, Dean, Sutton, Gregg S., Welch, Jeffrey
• Primary Examiner(s): Nguyen, Victor
• Application Number:
  US14/866,017
• Publication Number:
  US 20160008122A1
• Time in Patent Office: 1,320 Days
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/12159 Solid plugs; being solid before insertion
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/015 Stop means therefor
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/008 paraboloidal

Abstract

Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region.

Claims

1. An expandable structure deployable within an ostium of an atrium comprising:

an expandable stent having a first end, a second end, a radially compact delivery configuration, a generally cylindrical expanded configuration defining a longitudinal axis in which the expandable stent has an expanded radial dimension greater than a radially compact dimension of the radially compact delivery configuration, and

an expandable inner tubular member disposed within the expandable stent,

wherein the expandable stent has an opening including a valve structure adapted to prevent uncontrolled passage of fluid and including flaps sized and adapted to occlude the opening,

further comprising a tubular member disposed outside of the expandable stent.

2. The expandable structure of claim 1, wherein the expandable stent is self-expanding.

3. The expandable structure of claim 2, wherein the expandable stent is formed from shape memory alloy components.

4. The expandable structure of claim 2, wherein the expandable stent is formed from springs or elastic components.

5. The expandable structure of claim 1, wherein a removable component expands the expandable stent.

6. The expandable structure of claim 5, wherein the removable component is a balloon.

7. The expandable structure of claim 1, wherein the tubular membrane is made from biocompatible materials.

8. The expandable structure of claim 7, wherein the biocompatible materials include ePTFE.

9. The expandable structure of claim 1, wherein the expandable stent provides outward pressure adapted to reduce flow leakage about a periphery of the expandable structure.

10. The expandable structure of claim 1, further comprising an anterior portion and a posterior portion.

11. The expandable structure of claim 10, wherein the posterior portion is formed of a wire mesh or a braided or woven fabric.

12. The expandable structure of claim 10, wherein the posterior portion is flared with its diameter increasing along its axial length.

13. The expandable structure of claim 10, wherein the posterior portion has barbs distributed over at least a part of its exterior surface area.

14. The expandable structure of claim 13, wherein the barbs engage surrounding ostium walls to secure the expandable structure in position.

15. The expandable structure of claim 1, wherein the expandable inner tubular member includes an elastically sealed valve structure.