Methods and devices for conduit occlusion

• US 10,292,732 B2
• Filed: 09/27/2018
• Issued: 05/21/2019
• Est. Priority Date: 02/25/2004
• Status: Active Grant

• Current Assignee: Femasys, Inc.
• Original Assignee: Femasys, Inc.
• Inventors: Lee-Sepsick, Kathy, Paxton, Lani L. L., Marcus, Jeffrey A., Williams, Stephen N.
• Primary Examiner(s): Tran, Susan T
• Assistant Examiner(s): Craigo, William
• Application Number:
  US16/144,033
• Publication Number:
  US 20190046237A1
• Time in Patent Office: 236 Days
• Field of Search: None
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 17/42 Gynaecological or obstetrical instruments or methods ligaturing clamps or clips for the umbilical cord A61B17/122; curettage A61B17/320708; dilators A61M29/00
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/4225 Cervix uteri
• CPC Class Codes: A61B 2017/4233 Operations on Fallopian tubes, e.g. sterilization A61B2017/1125 takes precedence
• CPC Class Codes: A61F 2/954 for placing stents or stent-grafts in a bifurcation
• CPC Class Codes: A61F 6/225 transcervical
• CPC Class Codes: A61M 25/01 Introducing, guiding, advancing, emplacing or holding catheters A61M25/10 takes precedence

Abstract

The present invention comprises systems, methods and devices for the delivery of compositions for occluding or of means for opening conduits. The implantable occlusive material may be delivered pre-formed or in situ cured and, may be a resorbable material that supports tissue ingrowth that eventually replaces the material leaving little or no original material in place. The delivery system is positioned to allow for placement of the occlusive material into the body conduit. Use of delivery systems, methods and devices for re-opening an occluded body conduit are also included.

Claims

1. A method for occluding at least one fallopian tube in a mammal, comprising,

a) positioning at the cornua of at least one fallopian tube of a mammal, an end structure of at least one catheter so that a delivery end of the catheter is located within the uterine cornua and is at or near a tubal ostium, wherein the end structure maintains the delivery end in the uterine cornua and aids in localized delivery of the occlusive material composition;

b) delivering an effective amount of an occlusive material composition through and out the delivery end of the catheter so that a fallopian tube is occluded, wherein the occlusive material composition comprises a material that polymerizes after delivery of the occlusive material composition.

2. The method of claim 1, wherein the end structure comprises a nozzle, balloon, or a cup.

3. The method of claim 1, further comprising,

c) withdrawing the at least one catheter.

4. The method of claim 1, further comprising, imaging with sonography the uterus, the at least one fallopian tube or both, before the step a).

5. The method of claim 3, further comprising, imaging with sonography the uterus, the at least one fallopian tube or both, before step a) or after step c).

6. The method of claim 3, further comprising imaging with sonography the uterus, the at least one fallopian tube or both, before step a) and after step c).

7. A method for occluding two fallopian tubes in a mammal, comprising,

a) positioning at the cornua of each of two fallopian tubes of a mammal, an end structure of a catheter so that a delivery end of the catheter is located within the uterine cornua and is at or near a tubal ostium, wherein the end structure maintains the delivery end in the uterine cornua and aids in localized delivery of the occlusive material composition;

b) delivering an effective amount of an occlusive material composition through and out the delivery end of each of the cathetes so that a fallopian tube is occluded, wherein the occlusive material composition comprises a material that polymerizes after delivery of the occlusive material composition.

8. The method of claim 7, wherein the end structure comprises a nozzle, balloon, or a cup.

9. The method of claim 7, further comprising,

c) withdrawing the at least one catheter.

10. The method of claim 7, further comprising, imaging with sonography the uterus, the two fallopian tubes or both, before the step a).

11. The method of claim 9, further comprising, imaging with sonography the uterus, the two fallopian tubes or both, before step a) or after step c).

12. The method of claim 9, further comprising imaging with sonography the uterus, the two fallopian tubes or both, before step a) and after step c).

13. A method for delivering a fluid composition to at least one fallopian tubes in a mammal, comprising,

a) positioning at the cornua of at least one fallopian tube of a mammal, an end structure of at least one catheter so that a delivery end of the catheter is located within the uterine cornua and is at or near a tubal ostium, wherein the end structure maintains the delivery end in the uterine cornua and aids in localized delivery of the fluid composition;

b) delivering an effective amount of the fluid composition through and out the delivery end of the catheter so that at least a portion of the fluid composition is delivered to a fallopian tube.

14. The method of claim 13, wherein the end structure comprises a nozzle, balloon, or a cup.

15. The method of claim 13, further comprising,

c) withdrawing the at least one catheter.

16. The method of claim 13, further comprising, imaging with sonography the uterus, the at least one fallopian tube or both, before the step a).

17. The method of claim 15, further comprising, imaging with sonography the uterus, the at least one fallopian tube or both, before step a) or after step c).

18. The method of claim 15, further comprising imaging with sonography the uterus, the at least one fallopian tube or both, before step a) and after step c).