Combination therapy with peptide epoxyketones
First Claim
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1. A method of treating multiple myeloma in a patient, the method comprising administering to the patient in need of treatment a combination of:
- (a) melphalan, and (b) an effective amount of an epoxy ketone proteasome inhibitor having the structure of
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Abstract
The invention provides combination therapy, wherein one or more other therapeutic agents are administered agents are administered with peptide epoxyketones or a pharmaceutically acceptable salt thereof. Another aspect of the invention relates to treating cancer with a peptide epoxyketone administered in combination with another therapeutic agent.
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Citations
6 Claims
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1. A method of treating multiple myeloma in a patient, the method comprising administering to the patient in need of treatment a combination of:
- (a) melphalan, and (b) an effective amount of an epoxy ketone proteasome inhibitor having the structure of
- View Dependent Claims (2, 3, 4, 5)
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6. A method of treating multiple myeloma in a patient, the method consisting essentially of administering to the patient in need of treatment a combination of:
- (a) melphalan, and (b) an effective amount of an epoxy ketone proteasome inhibitor having the structure of
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