Transcutaneous analyte sensor

• US 10,610,103 B2
• Filed: 08/16/2019
• Issued: 04/07/2020
• Est. Priority Date: 06/21/2005
• Status: Active Grant

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Brister, Mark C., Pryor, Jack, Nolting, John, Leach, Jacob S., Pestana, Luis, Quintana, Nelson, Swanson, Vance, Goode, Jr., Paul V., Thrower, James Patrick
• Primary Examiner(s): Jang, Christian
• Application Number:
  US16/543,338
• Publication Number:
  US 20190365227A1
• Time in Patent Office: 235 Days
• CPC Class Codes: A61B 2560/0214 of power generation or supply
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 2562/08 Sensors provided with means for identification, e.g. barcodes or memory chips
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/1411 by percutaneous method, e.g. by lancet
• CPC Class Codes: A61B 5/14507 specially adapted for measuring characteristics of body fluids other than blood devices for taking samples of body liquids A61B10/0045
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150534 Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
• CPC Class Codes: A61B 5/6832 using adhesives A61B5/259 takes precedence
• CPC Class Codes: A61B 5/6833 Adhesive patches
• CPC Class Codes: A61B 5/6848 Needles
• CPC Class Codes: A61B 5/6849 in combination with a needle set
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: G16Z 99/00 Subject matter not provided for in other main groups of this subclass
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Claims

1. A system for measuring an analyte concentration in a host, the system comprising:

a sensor system comprising;

a first component comprising a transcutaneous analyte sensor, wherein the transcutaneous analyte sensor is configured to measure a signal indicative of an analyte concentration in the host, wherein the transcutaneous analyte sensor comprises;

an in vivo portion configured for insertion and existence within a living body of the host during sensor use; and

an ex vivo portion configured to remain outside the living body of the host during sensor use; and

a second component comprising sensor electronics configured to operably connect with the transcutaneous analyte sensor during sensor use, wherein the sensor electronics comprise;

one or more memories configured to store;

data representative of analyte concentrations derived from signal measurements from the transcutaneous analyte sensor; and

sensor calibration information for calibration of the transcutaneous analyte sensor without requiring a reference analyte value;

wherein the first component is unconnected to the second component in a first state, wherein during a second state the first component is configured to be connected to the second component by the host to form an assembly prior to the assembly being affixed to the host for sensor insertion.

2. The system for measuring an analyte concentration in a host of claim 1, wherein the system is configured to have a sensor lifetime of about 14 days.

3. The system for measuring an analyte concentration in a host of claim 1, wherein the sensor electronics is configured to work in concert with the transcutaneous analyte sensor to generate analyte concentration measurements.

4. The system for measuring an analyte concentration in a host of claim 1, wherein the sensor electronics are disposed inside a housing having a height of from 0.075 inches to 0.2 inches.

5. The system for measuring an analyte concentration in a host of claim 1, wherein the sensor electronics further comprise:

a radio frequency module.

6. The system for measuring an analyte concentration in a host of claim 5, wherein the sensor electronics further comprise:

a temperature sensor configured to generate temperature data for temperature compensation of a value associated with analyte concentration; and

an internal power source, wherein the internal power source comprises a disposable battery having a height from 0.08 to 0.125 inches.

7. The system of claim 6, wherein the disposable battery supplies power for a bias voltage applied to the transcutaneous analyte sensor by the sensor electronics.

8. The system for measuring an analyte concentration in a host of claim 5, the sensor system further comprising:

a receiver comprising;

a processor configured to cause interrogation of the radio frequency module, and to process data received from the radio frequency module by the interrogation, wherein the interrogation comprises use of inductive coupling; and

a display configured to display an estimated analyte concentration value associated with the processed data.

9. The system of claim 8, wherein the radio frequency module is configured to transmit information representative of the analyte concentration to the receiver in response to the receiver interrogating the sensor electronics.

10. The system of claim 9, wherein the receiver is configured to provide inductive power to the sensor electronics during the interrogation.

11. The system of claim 8, wherein the receiver is configured to supply inductive power for data retrieval from the sensor electronics.