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Peptides for enhanced cell attachment and growth

  • US 20050106727A1
  • Filed: 09/26/2003
  • Published: 05/19/2005
  • Est. Priority Date: 08/15/2003
  • Status: Active Grant
First Claim
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1. A cell adhesion promoting (CAP) peptide-modified polymer composition useful for promoting cell attachment or growth, comprising a polymer surface made of/with a cell adhesion resistant (CAR) material to which one or more peptides are covalently bound, forming a peptide-modified CAP surface, which peptides/surface promote[s]:

  • (i) attachment of cells, which cells substantially do not attach to said CAR surface in the absence of said peptides and, (ii) optionally, growth, differentiation or enhanced survival of cells that have attached to the peptide-modified surface, which cells substantially do not attach to, grow, differentiate or manifest enhanced survival on, said CAR surface in the absence of said peptides.

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