Ion imbalance detector
First Claim
1. A system comprising:
- a pulse generator configured to generate an electrical stimulation;
an electrode configured to deliver the electrical stimulation to a tissue in a patient;
a sensor configured to detect a response of the tissue to the electrical stimulation; and
a processor configured to determine a concentration of ions in extracellular fluid of the patient as a function of the response.
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Accused Products
Abstract
In general, the invention is directed to methods and devices for determining an ion concentration in the extracellular fluid of a patient. As examples, the ion may be one or more of potassium, sodium, chloride, or calcium. A system includes an electrode deployed in or near a tissue, such as a skeletal muscle, of the patient. A pulse generator supplies one or more stimulations to the tissue, and a sensor, such as an accelerometer, detects the response of the tissue to the stimulations. A processor determines a concentration of ions in the extracellular fluid as a function of the response. The system may detect an ion imbalance based upon the determined concentration of ions.
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Citations
44 Claims
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1. A system comprising:
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a pulse generator configured to generate an electrical stimulation;
an electrode configured to deliver the electrical stimulation to a tissue in a patient;
a sensor configured to detect a response of the tissue to the electrical stimulation; and
a processor configured to determine a concentration of ions in extracellular fluid of the patient as a function of the response. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 28, 29)
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17. A method comprising:
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delivering an electrical stimulation to a tissue in a patient;
detecting a response of the tissue to the electrical stimulation; and
determining a concentration of ions in extracellular fluid of the patient as a function of the response. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
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30. A computer-readable medium comprising instructions that cause a programmable processor to:
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control a pulse generator to deliver an electrical stimulation to a tissue in a patient;
receive from a sensor a signal indicative of a response of the tissue to the electrical stimulations; and
determine a concentration of ions in extracellular fluid of the patient as a function of the response. - View Dependent Claims (31, 32, 33, 34, 35, 36, 37)
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38. A method comprising:
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delivering an electrical stimulation to a tissue in a patient;
detecting a response of the tissue to the electrical stimulations; and
storing a relationship between a concentration of ions in extracellular fluid of the patient and the response. - View Dependent Claims (39, 40, 41)
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42. A computer-readable medium comprising instructions that cause a programmable processor to:
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control a pulse generator to deliver an electrical stimulation to a tissue in a patient;
receive from a sensor a signal indicative of a response of the tissue to the electrical stimulations; and
store a relationship between a concentration of ions in extracellular fluid of the patient and the response. - View Dependent Claims (43, 44)
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Specification