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Method and apparatus for glucose monitoring

  • US 20070105176A1
  • Filed: 09/28/2006
  • Published: 05/10/2007
  • Est. Priority Date: 09/28/2005
  • Status: Active Grant
First Claim
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1. A device for sensing an analyte, said device comprising:

  • a ligand selected from the group consisting of dextran, a functionalized polymer, and a functionalized nano-particle;

    a first fluorophore selected from the group consisting of a fluoresceine, a rhodamine, a cyanine, an alexafluore, and combinations thereof;

    a sugar-binding lectin selected from the group consisting of Concanavalin A, glucose binding protein, glucose oxidase, glucose apo-oxidase, and combinations thereof; and

    a second fluorophore selected from the group consisting of a fluoresceine, a rhodamine, a cyanine, an alexafluore, and combinations thereof, wherein the first fluorophore is linked to the ligand and the second fluorophore is linked to the sugar-binding lectin and wherein the first fluorophore is a reference fluorophore and the second fluorophore is quenchable fluorophore and the second fluorophore is a reference fluorophore.

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