Analyte sensing and response system
First Claim
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1. An infusion system for infusing a fluid into a user, comprising:
- a sensor configured to monitor concentration of an analyte in the user and to generate a sensor output signal based on the monitored concentration, wherein the sensor output signal is used to generate a processor input signal;
a fading memory proportional derivative processor configured to process the processor input signal and to generate a processor output signal; and
a fluid delivery system configured to infuse fluid into the user in a manner based at least partially on the processor output signal.
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Abstract
Electrochemical systems for measuring an analyte concentration, and correcting any surplus or deficiency in the measured concentration. More specifically, systems for measuring an analyte level in a fluid with an implantable sensor, processing the measurements with an algorithm, and determining an appropriate fluid infusion rate in response to the measurements.
136 Citations
24 Claims
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1. An infusion system for infusing a fluid into a user, comprising:
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a sensor configured to monitor concentration of an analyte in the user and to generate a sensor output signal based on the monitored concentration, wherein the sensor output signal is used to generate a processor input signal; a fading memory proportional derivative processor configured to process the processor input signal and to generate a processor output signal; and a fluid delivery system configured to infuse fluid into the user in a manner based at least partially on the processor output signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method of determining a fluid infusion rate for infusing a fluid into a user, comprising:
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monitoring concentration of an analyte in the user and generating a sensor output signal based on the monitored concentration; using the sensor output signal to generate a processor input signal; processing the processor input signal using a fading memory proportional derivative algorithm to generate a processor output signal; and determining the fluid infusion rate based at least partially on the processor output signal. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A method of controlling concentration of an analyte in a mammal, comprising:
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repeatedly measuring concentration of an analyte in a mammal with a sensor implanted in the mammal; using an algorithm to compute a fluid delivery rate based on the measured analyte concentration; and delivering fluid to the mammal at the computed fluid delivery rate; wherein the algorithm computes the fluid delivery rate based on; a current analyte proportional error; prior analyte proportional errors, wherein more recent prior analyte proportional errors are weighted more heavily than more remote prior analyte proportional errors; a current analyte derivative error; and prior analyte derivative errors, wherein more recent prior analyte derivative errors are weighted more heavily than more remote prior analyte derivative errors. - View Dependent Claims (20, 21, 22, 23, 24)
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Specification