Fluid Delivery With In Vivo Electrochemical Analyte Sensing
First Claim
Patent Images
1. An apparatus comprising:
- a subcutaneously insertable element that comprises a proximal portion and a distal portion, the distal portion being configured for subcutaneous placement within a human body; and
a sensor that electrochemically interacts with one or more analytes and generates a signal that is representative of a concentration of the one or more analytes, the sensor being disposed on or within the distal portion of the subcutaneously insertable element;
a processor that receives and processes the signal from the sensor to determine the concentration of the one or more analytes within the human body; and
an external device that comprises the processor and that is in mechanical contact with the proximal portion of the subcutaneously insertable element.
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Abstract
One or more therapeutic fluids, such as for example insulin can be delivered to a body. In addition or alternatively, the concentrations of one or more analytes can be measured in vivo. A feedback process can be used to regulate levels of the one or more analytes based on the measurements via delivery of the one or more therapeutic fluids. Related systems, apparatus, methods, and/or articles are also described.
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Citations
24 Claims
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1. An apparatus comprising:
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a subcutaneously insertable element that comprises a proximal portion and a distal portion, the distal portion being configured for subcutaneous placement within a human body; and a sensor that electrochemically interacts with one or more analytes and generates a signal that is representative of a concentration of the one or more analytes, the sensor being disposed on or within the distal portion of the subcutaneously insertable element; a processor that receives and processes the signal from the sensor to determine the concentration of the one or more analytes within the human body; and an external device that comprises the processor and that is in mechanical contact with the proximal portion of the subcutaneously insertable element. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method for fabrication of electrodes of a sensor on a surface of subcutaneously insertable element, the method comprising:
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forming grooves on the surface of the subcutaneously insertable element; depositing conductive material within the grooves; temporarily covering at least one of the grooves to prevent contamination of the conductive material; depositing an electrochemical reagent on the uncovered position of the grooves; and removing the covering from the at least one of the grooves.
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19. A method comprising:
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electrochemically detecting, with a sensor secured to a distal end of a subcutaneously insertable element, a concentration of an analyte within a human body; and dispensing a therapeutic fluid to the human body. - View Dependent Claims (20, 21, 22, 23, 24)
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Specification