METHODS AND SYSTEMS FOR TREATING A PSYCHOTIC DISORDER
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Abstract
Methods of treating a psychotic disorder include applying at least one stimulus to a stimulation site within a patient with an implanted stimulator in accordance with one or more stimulation parameters configured to treat the psychotic disorder. Systems for treating a psychotic disorder include a stimulator configured to apply at least one stimulus to a stimulation site within a patient in accordance with one or more stimulation parameters configured to treat the psychotic disorder.
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Citations
37 Claims
- 1. -20. (canceled)
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21. A method of treating a psychotic disorder, said method comprising:
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applying at least one stimulus to a stimulation site within a patient with an implanted stimulator in accordance with one or more stimulation parameters to treat said psychotic disorder; and sensing at least one indicator related to said psychotic disorder and using said at least one sensed indicator to adjust one or more of said stimulation parameters; wherein said stimulation site comprises at least one or more of a frontal lobe, temporal lobe, cingulate gyrus, substantia nigra, thalamus, amygdala, hippocampus, ventral tegmental area, and nucleus accumbens, and locus coeruleus; and wherein said at least one indicator comprises at least one of a discharge frequency of a neural population in said stimulation site, a chemical level of said stimulation site, a neurotransmitter level, a hormone level, a drug level within said patient, a change in blood plasma, a change in interstitial fluid, a change in cerebrospinal fluid, a dopamine level, an interleukin level, a cytokine level, a lymphokine level, a chemokine level, a growth factor level, an electrolyte level, and an enzyme level.
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Specification