Method and apparatus for measuring sample reaction results on biosensor

• US 20100243481A1
• Filed: 07/05/2006
• Published: 09/30/2010
• Est. Priority Date: 08/08/2005
• Status: Active Grant

• Current Assignee: Osang Healthcare Co., Ltd.
• Original Assignee: INFOPIA CO., LTD
• Inventors: Yoo, Jin-a, Lee, Sung-dong, Suk, Hong-seong, Bae, Byeong-woo
• Granted Patent: US 7,897,033 B2
• Time in Patent Office: Days
• US Class Current: 205/792
• CPC Class Codes: C12Q 1/006 for glucose
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52

Abstract

Disclosed is a method of measuring sample reaction results on a biosensor having a working electrode and other electrodes, including: applying voltage between the working electrode and each of the other electrodes and detecting the amount of current flowing through the working electrode to determine whether or not a sample is injected; applying voltage between the working electrode and one of the other electrodes and re-detecting the amount of current flowing through the working electrode; and acquiring and displaying a concentration value as a sample reaction result corresponding to the amount of detected current.

Claims

1. A method of measuring sample reaction results on a biosensor having a working electrode and other electrodes, comprising:

applying voltage between the working electrode and each of the other electrodes and detecting the amount of current flowing through the working electrode to determine whether or not a sample is injected;

applying voltage between the working electrode and one of the other electrodes and re-detecting the amount of current flowing through the working electrode; and

acquiring and displaying a concentration value as a sample reaction result corresponding to the amount of detected current.

2. The method of claim 1, wherein the concentration value is acquired from a concentration value table stored in a memory.

3. The method of claim 1, wherein the concentration value is acquired by operating a predetermined factor to the amount of re-detected current.

4. A method of measuring sample reaction results on a biosensor having at least a working electrode, a checking electrode, and a counter electrode, comprising:

applying voltage between the checking electrode and the working electrode, and between the counter electrode and the working electrode, and detecting the amount of currents flowing through the working electrode, and a time interval between times when the amount of two currents is detected;

determining whether or not a sample is injected by comparing the amount of detected currents and the detected time interval with predetermined threshold values;

applying voltage between the working electrode and the counter electrode and re-detecting the amount of current flowing through the working electrode; and

acquiring and displaying a concentration value as a sample reaction result corresponding to the amount of re-detected current.

5. The method of claim 4, wherein the concentration value is acquired from a concentration value table stored in a memory.

6. The method of claim 4, wherein the concentration value is acquired by operating a predetermined factor to the amount of re-detected current.

7. An apparatus for measuring sample reaction results on a biosensor having a working electrode and other electrodes, comprising:

switches connecting a plurality of electrodes of the biosensor coupled to the apparatus to a ground terminal;

an amplifier connected at its one terminal to a voltage source and at another terminal to the working electrode of the biosensor to detect the amount of current flowing through the working electrode; and

a microprocessor controlling the switches so that voltage can be applied between the working electrode and each of the electrodes upon coupling of a sensor strip, detecting the amount of current flowing through the working electrode to determine whether or not a sample is injected, controlling the switches so that voltage can be applied between the working electrode and any one of the electrodes, re-detecting the amount of current flowing through the working electrode, acquiring and displaying a concentration value as a sample reaction result corresponding to the amount of re-detected current on a display unit.

8. The apparatus of claim 7, wherein the microprocessor includes a memory storing concentration values as sample reaction results corresponding to the amount of re-detected current.

9. The apparatus of claim 7, wherein the microprocessor operates the amount of re-detected current to a predetermined factor to acquire a concentration value as a sample reaction result.

10. The apparatus of claim 7, wherein the microprocessor indicates a sample recognition error if the amount of two currents detected to determine whether or not the sample is injected, and a time interval between times when the amount of the two currents is detected fail to meet a predetermined condition.

11. The apparatus of claim 8, wherein the microprocessor indicates a sample recognition error if the amount of two currents detected to determine whether or not the sample is injected, and a time interval between times when the amount of the two currents is detected fail to meet a predetermined condition.

12. The apparatus of claim 9, wherein the microprocessor indicates a sample recognition error if the amount of two currents detected to determine whether or not the sample is injected, and a time interval between times when the amount of the two currents is detected fail to meet a predetermined condition.