DEVICES AND TECHNIQUES ASSOCIATED WITH DIAGNOSTICS, THERAPIES, AND OTHER APPLICATIONS, INCLUDING SKIN-ASSOCIATED APPLICATIONS
First Claim
1. A device for analysis of an extractable medium from a subject, the device comprising:
- a support structure constructed and arranged to be positioned proximate the skin of the subject;
means associated with the support structure for accessing the extractable medium from and/or through the skin of the subject at an access site;
a pressure regulator supported by the support structure, able to create a pressure differential across the skin at least a portion of the access site;
a sensor supported by the support structure, for determining at least one condition of the extractable medium from the subject; and
a signal generator supported by the support structure, for generating a signal relating to the condition of the medium determined by the sensor.
6 Assignments
0 Petitions
Accused Products
Abstract
The present invention generally relates to devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications, for example, devices for delivering and/or withdrawing fluid from subjects, e.g., through the skin. In some embodiments, the device includes a system for accessing an extractable medium from and/or through the skin of the subject at an access site, and a pressure regulator supported by a support structure, able to create a pressure differential across the skin at least a portion of the access site. The device may also include, in some cases, a sensor supported by the support structure for determining at least one condition of the extractable medium from the subject, and optionally a signal generator supported by the support structure for generating a signal relating to the condition of the medium determined by the sensor.
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Citations
47 Claims
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1. A device for analysis of an extractable medium from a subject, the device comprising:
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a support structure constructed and arranged to be positioned proximate the skin of the subject; means associated with the support structure for accessing the extractable medium from and/or through the skin of the subject at an access site; a pressure regulator supported by the support structure, able to create a pressure differential across the skin at least a portion of the access site; a sensor supported by the support structure, for determining at least one condition of the extractable medium from the subject; and a signal generator supported by the support structure, for generating a signal relating to the condition of the medium determined by the sensor. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. A device for analysis of an extractable medium from a subject, the device comprising:
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a support structure constructed and arranged to be positioned proximate the skin of the subject; a fluid transporter for accessing the extractable medium from and/or through the skin of the subject at an access site; a pressure regulator supported by the support structure, able to create a pressure differential across the skin at least a portion of the access site; a sensor supported by the support structure, for determining at least one condition of the extractable medium from the subject; and a signal generator supported by the support structure, for generating a signal relating to the condition of the medium determined by the sensor.
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32. A device for analysis of an extractable medium from a subject, the device comprising:
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means for accessing the extractable medium from and/or through the skin of the subject at an access site; a pressure regulator, able to create a pressure differential across the skin at least a portion of the access site; a sensor for determining at least one condition of the extractable medium from the subject; and a signal generator for generating a signal relating to the condition of the medium determined by the sensor.
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33. A device for analysis of an extractable medium from a subject, the device comprising:
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means for accessing the extractable medium from skin and/or from beneath the skin of the subject at an access site; a pressure differential chamber able to create a pressure differential across the skin in at least a portion of the access site in the absence of a piston pump associated with the chamber; a sensor for determining at least one condition of the extractable medium from the subject; and a signal generator for generating a signal relating to the condition of the medium determined by the sensor.
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34. A method for analyzing an extractable medium from a subject, comprising:
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positioning an analysis device, comprising a pathway, adjacent the skin of the subject and, while the device is adjacent the skin; activating an access component of the device to connect the extractable medium with the pathway of the device; activating a pressure controller of the device to urge the extractable medium into the device via the pathway; exposing the medium to a sensor of the device and determining at least one condition of the extractable medium from the subject; and generating a signal relating to the condition of the medium determined by the sensor.
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35. A device applicable to a site proximate the skin of a subject, comprising:
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an agent that reacts or interacts with an analyte to be detected and generates a signal that can be detected visually, by feel, by smell, or by taste, wherein the agent that reacts with or interacts with an analyte and the signaling agent can be the same or different, and wherein the signal can vary as a function of an attribute of the analyte, producing a signal that can be analyzed qualitatively.
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36. A device applicable to a site proximate the skin of a subject, comprising:
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an agent that reacts or interacts with an analyte to be detected and generates a signal that can be detected visually, by feel, by smell, or by taste, wherein the agent that reacts or interacts with an analyte and the signaling agent can be the same or different, and wherein the device acquires fluid from the subject and transports the fluid from a site of acquisition to a site of analysis for reaction.
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37. A device applicable to a site proximate the skin of a subject, wherein the device determines a physical condition of a subject and produces a signal related to the condition, the signal not readily understandable by the subject.
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38. A method, comprising:
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providing a device at a site proximate the skin of a subject, wherein the device determines a physical condition of a subject and produces a signal related to the condition; acquiring a representation of the signal; and transporting the representation of the signal to an entity that analyzes the representation.
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39. A method comprising:
providing a plurality of analysis sites proximate the skin of a subject, including at least a first analysis site that generates a first signal related to a first physical condition of the subject and a second analysis site that generates a second signal related to a second physical condition of the subject.
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40. A method comprising:
providing a reaction site proximate the skin of a subject comprising a reactive agent that reacts or interacts with an analyte to generate an signal in the form of an icon.
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41. A device applicable to a site proximate the skin of a subject to determine a condition of the subject, comprising:
a first component and a second component connected to the first component for application to the site and separable from the first component after application to the site, wherein the first component can be activated to acquire a bodily fluid of the subject, and the second component comprises an agent that reacts or interacts with an analyte to be detected and generates a signal that can be detected visually, by feel, by smell, or by taste.
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42. A device wearable by a subject, comprising an agent that reacts or interacts with an analyte in saliva of the subject to generate a signal.
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43. A device applicable to a site proximate the skin of a subject, the device comprising an agent that reacts or interacts with an analyte to be detected to generate a signal that can be detected visually, by feel, by smell, or by taste,
wherein the device comprises a membrane comprising the agent that participates in generation of the signal, the membrane being selective to one or more of passage of an analyte and/or an analyte indicator, and reaction with an analyte and/or an analyte indicator.
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44. A method comprising applying, proximate the skin of a subject in need of emergency care, a device comprising a reactive agent that reacts or interacts with an analyte to generate a signal indicative of a condition of the subject.
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45. A method, comprising:
applying, to a solution containing a plurality of first particles of a first color and a plurality of second particles of a second color, an electric field and/or a magnetic field sufficient to cause a change in color of the solution.
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46. A method comprising:
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exposing, to a sample, a population of particles including at least a first sub-population having a first determinable characteristic and a second sub-population having a second determinable characteristic; allowing at least some particles of the first sub-population of particles to bind a component of the sample via a binding partner, wherein the second sub-population of particles remains essentially unbound to the component, such that the ratio of the number of particles from the first sub-population bound to the component, to the number of particles from the second sub-population bound to the component, is at least 5;
1;separating the particles bound to the component from those not bound; and determining a characteristic of the sample by determining the separation.
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47. A method comprising:
determining a characteristic of a sample by visualizing a color change effected by a change in population of particles of different color upon preferential binding of particles of one color to a component of the sample via a binding partner.
Specification