Preparation of Vaccines Using Photosensitizer and Light
First Claim
Patent Images
1. A method of making a vaccine for preventing the replication of live tumor cells in a mammal comprising the steps of:
- removing a tumor from the mammal;
purifying at least some of the tumor cells from the tumor;
inactivating the tumor cells by exposing the tumor cells to an endogenous photosensitizer and light at a sufficient wavelength to prevent replication of the tumor cells but not substantially destroy the antigenic determinants of the tumor cells; and
suspending the inactivated tumor cells in a suspension solution.
2 Assignments
0 Petitions
Accused Products
Abstract
Methods are provided for treating a vaccine containing infectious particles which may be viral, bacterial, and/or cellular in nature. Preferred methods include the steps of adding an effective, non-toxic amount of an endogenous photosensitizer to the fluid and exposing the fluid to photoradiation sufficient to inactivate the infectious particles but not enough to damage the antigenic characteristics of the infectious particles.
-
Citations
6 Claims
-
1. A method of making a vaccine for preventing the replication of live tumor cells in a mammal comprising the steps of:
-
removing a tumor from the mammal; purifying at least some of the tumor cells from the tumor; inactivating the tumor cells by exposing the tumor cells to an endogenous photosensitizer and light at a sufficient wavelength to prevent replication of the tumor cells but not substantially destroy the antigenic determinants of the tumor cells; and suspending the inactivated tumor cells in a suspension solution. - View Dependent Claims (2, 3, 4, 5, 6)
-
Specification