FLUID FLOW OCCLUDER AND METHODS OF USE FOR MEDICAL TREATMENT SYSTEMS

• US 20110098635A1
• Filed: 01/23/2009
• Published: 04/28/2011
• Est. Priority Date: 01/23/2008
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: DEKA Research & Development
• Inventors: Overson, Jason M., Bodwell, Jesse T., Helmore, Simon C., Dale, James D.
• Granted Patent: US 9,028,440 B2
• Time in Patent Office: Days
• US Class Current: 604/29
• CPC Class Codes: A61M 1/14 Dialysis systems; Artificial kidneys; Blood oxygenators semi-permeable membranes characterised by the material, manufacturing processes therefor B01D71/00; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
• CPC Class Codes: A61M 1/1522 the interface being evacuated interfaces to enhance contact
• CPC Class Codes: A61M 1/1524 the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/153 the cassette being adapted for heating or cooling the treating fluid, e.g. the dialysate or the treating gas
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/159 specially adapted for peritoneal dialysis
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1601 Control or regulation
• CPC Class Codes: A61M 1/1623 Disposition or location of membranes relative to fluids
• CPC Class Codes: A61M 1/1629 with integral heat exchanger
• CPC Class Codes: A61M 1/1631 having non-tubular membranes, e.g. sheets
• CPC Class Codes: A61M 1/166 Heating for sterilisation A61M1/1686
• CPC Class Codes: A61M 1/1694 with recirculating dialysing liquid
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/281 Instillation other than by gravity
• CPC Class Codes: A61M 1/282 Operational modes
• CPC Class Codes: A61M 1/288 Priming priming in extracorporeal blood circuits A61M1/3643
• CPC Class Codes: A61M 2039/1066 having protection means, e.g. sliding sleeve to protect connector itself, shrouds to protect a needle present in the connector, protective housing, isolating sheath
• CPC Class Codes: A61M 2205/12 : with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/121 : interface between cassette and base
• CPC Class Codes: A61M 2205/122 : using evacuated interfaces to enhance contact
• CPC Class Codes: A61M 2205/123 : with incorporated reservoirs
• CPC Class Codes: A61M 2205/127 : with provisions for heating or cooling
• CPC Class Codes: A61M 2205/128 : with incorporated valves
• CPC Class Codes: A61M 2205/13 : with means for the detection of operative contact with patient, e.g. lip sensor
• CPC Class Codes: A61M 2205/14 : Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 2205/3306 : Optical measuring means
• CPC Class Codes: A61M 2205/3331 : Pressure; Flow
• CPC Class Codes: A61M 2205/3334 : Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3379 : Masses, volumes, levels of fluids in reservoirs, flow rates
• CPC Class Codes: A61M 2205/36 : related to heating or cooling
• CPC Class Codes: A61M 2205/502 : User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/6036 : characterised by physical shape, e.g. array of activating switches
• CPC Class Codes: A61M 2209/08 : Supports for equipment
• CPC Class Codes: A61M 39/1011 : Locking means for securing connection; Additional tamper safeties A61M39/16 takes precedence
• CPC Class Codes: A61M 39/105 : Multi-channel connectors or couplings, e.g. for connecting multi-lumen tubes multi-channel connectors in general F16L37/56
• CPC Class Codes: A61M 39/20 : Closure caps or plugs for connectors or open ends of tubes
• CPC Class Codes: A61M 39/28 : Clamping means for squeezing flexible tubes, e.g. roller clamps tube strippers A61M1/83
• CPC Class Codes: A61M 39/281 : Automatic tube cut-off devices, e.g. squeezing tube on detection of air
• CPC Class Codes: A61M 5/16809 : by repeated filling and emptying of an intermediate volume pressure infusion using positive displacement pumps A61M5/142
• CPC Class Codes: A61M 5/16813 : by controlling the degree of opening of the flow line
• CPC Class Codes: A61M 5/16827 : controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: F04B 43/0054 : particularities of the flexible members
• CPC Class Codes: F04B 43/02 : having plate-like flexible members, e.g. diaphragms F04B43/14 takes precedence
• CPC Class Codes: F04B 43/073 : the actuating fluid being controlled by at least one valve
• CPC Class Codes: F04B 43/08 : having tubular flexible members F04B43/12 takes precedence
• CPC Class Codes: F04B 43/086 : with two or more tubular flexible members in parallel F04B43/1136 takes precedence
• CPC Class Codes: F04B 53/22 : Arrangements for enabling ready assembly or disassembly
• CPC Class Codes: G16H 20/40 : relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
• CPC Class Codes: G16H 40/63 : for local operation
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

An occluder (147), and methods for occlusion, that employs first and second opposed occluding members (165) associated with each other, a tube contacting member (161) connected to, or comprising at least a portion of, at least one of the first and second occluding members, and a force actuator (166) constructed and positioned to apply a force to at least one of the first and second occluding members. Application of the force by the force actuator may cause the tube contacting member to move between a tube occluding and an open position. A release member (169) may be configured and positioned to enable an operator to manually move the tube contacting member from the tube occluding position to the open position even with no force applied to the occluding member by the force actuator. In one embodiment, the force actuator may apply a force sufficient to bend both the first and second occluding members, so that upon application of the force by the force actuator (such as an air bladder), the first and second occluding members (e.g., spring plates pivotal Iy connected at opposite ends) bend and the tube contacting member may move between a tube occluding and an open position.

Claims

1. An automated peritoneal dialysis system comprising:

a reusable cycler that is constructed and arranged for coupling to a disposable fluid handling cassette containing at least one pumping chamber, wherein

the disposable fluid handling cassette is configured to be connected in fluid communication with the peritoneum of a patient via a first collapsible tube and with a second source and/or destination via a second collapsible tube; and

an occluder configured and positioned within the cycler to selectively occlude the first collapsible tube while not occluding the second collapsible tube.

2. The automated peritoneal dialysis system as recited in claim 1, wherein the occluder is configured to occlude a plurality of collapsible tubes.

3. The automated peritoneal dialysis system as recited in claim 2, wherein the disposable fluid handling cassette comprises a generally planar body having at least one pump chamber formed as a depression in a first side of the body and a plurality of flowpaths for fluid;

a patient line port located at a first end of the body arranged for connection to the first collapsible tube, the patient line port being in fluid communication with the at least one pump chamber via at least one flowpath; and

a solution line port located at a second end of the body opposite the first end, and arranged for connection to the second collapsible tube, the solution line port being in fluid communication with the at least one pump chamber via at least one flowpath.

4. The automated peritoneal dialysis system as recited in claim 3, wherein the fluid handling cassette further comprises a patient drain line port located at the first end of the body arranged for connection to a third collapsible tube, the patient drain line port being in fluid communication with the at least one pump chamber via at least one flowpath, and wherein the occluder is configured and positioned within the cycler to selectively occlude the first and third collapsible tubes while not occluding the second collapsible tube.

5. The automated peritoneal dialysis system as recited in claim 4, wherein the fluid handling cassette comprises a plurality of solution line ports, each located at the second end of the body opposite the first end, and each arranged for connection to a collapsible tube, each of the solution line ports being in fluid communication with the at least one pump chamber via at least one flowpath, and wherein the occluder is configured and positioned within the cycler to selectively occlude the first and third collapsible tubes while not occluding the plurality of collapsible tubes connected to the solution line ports.

6. The automated peritoneal dialysis system as recited in claim 1, wherein the occluder comprises:

a first and a second opposed occluding members;

a tube contacting member connected to, or comprising at least a portion of, at least one of the first and second occluding members; and

a force actuator constructed and positioned to apply a force to at least one of the first and second occluding members to increase a distance between the first and second occluding members in a region where the first and second occluding members are in opposition,

wherein upon application of the force by the force actuator to increase the distance, the tube contacting member moves between a tube occluding and an open position.

7. The automated peritoneal dialysis system as recited in claim 1, wherein the occluder comprises:

a resilient occluding member;

a tube contacting member connected to, or comprising at least a portion of the occluding member;

a force actuator controlled by a microprocessor based control system constructed and positioned to apply a force to bend the occluding member to move the tube contacting member from a tube occluding position to an open position; and

a release member configured and positioned to enable an operator to manually move the tube contacting member from the tube occluding position to the open position even with no force applied to the occluding member by the force actuator.

8. The automated peritoneal dialysis system as recited in claim 1, wherein the occluder comprises:

a first and a second opposed occluding members pivotally connected to each other;

a tube contacting member connected to, or comprising at least a portion of, at least one of the first and second occluding members; and

a force actuator constructed and positioned to apply a force to at least one of the first and second occluding members,

wherein upon application of the force by the force actuator, the tube contacting member moves between a tube occluding and an open position.

9. The automated peritoneal dialysis system as recited in claim 1, wherein the occluder comprises:

a first and a second opposed resilient occluding members;

a tube contacting member connected to, or comprising at least a portion of, at least one of the first and second occluding members; and

a single force actuator constructed and positioned to apply a force sufficient to bend both the first and second occluding members,

wherein upon application of the force by the force actuator to bend the first and second occluding members, the tube contacting member moves between a tube occluding and an open position.

10. The automated peritoneal dialysis system as recited in claim 8, wherein the occluding members are spring plates pivotally connected together at opposite first and second ends

11. The automated peritoneal dialysis system as recited in claim 10, wherein the tube contacting member comprises a pinch head connected to the spring plates at the first ends and wherein the second ends of the spring plates are affixed directly or indirectly to a housing to which the occluder is connected.

12. The peritoneal dialysis system as recited in claim 6, wherein the force actuator is controlled by a microprocessor based control system.

13. The peritoneal dialysis system as recited in claim 6, wherein the force actuator comprises an inflatable bladder positioned between the first and second occluding members.

14. The peritoneal dialysis system as recited in claim 6, wherein application of the force by the force actuator moves the tube contacting member from a tube occluding position to an open position that allows flow between the peritoneum of the patient and the at least one pump chamber.

15. The peritoneal dialysis system as recited in claim 1, wherein the reusable cycler comprises a door.

16. The peritoneal dialysis system as recited in claim 15, wherein the door comprises a guide for the first collapsible tube.

17. The peritoneal dialysis system as recited in claim 15, wherein the door comprises an occluder stop to aid in occluding the first collapsible tube.

18. An occluder for occluding at least one collapsible tube of a medical infusion device, comprising:

a first and a second opposed occluding members;

a tube contacting member connected to, or comprising at least a portion of, at least one of the first and second occluding members; and

a force actuator constructed and positioned to apply a force to at least one of the first and second occluding members to increase a distance between the first and second occluding members in a region where the first and second occluding members are in opposition,

wherein upon application of the force by the force actuator to increase the distance, the tube contacting member moves between a tube occluding and an open position.

24. The occluder as recited in claim 18, wherein the occluding members are resilient, and wherein the force actuator is a force to bend at least one of the first and second occluding members.

29. The occluder as recited in claim 18, wherein the force actuator is controlled by a microprocessor based control system.

30. The occluder as recited in claim 18, wherein the force actuator comprises an inflatable bladder positioned between the first and second occluding members.

31. The occluder as recited in claim 18, wherein application of the force by the force actuator moves the tube contacting member from a tube occluding position to an open position.

32. The occluder as recited in claim 18, further comprising a release member positioned between the first and second occluding members to enable an operator to manually move the tube contacting member from the tube occluding position to the open position even with no force applied to the occluding member by the force actuator.

34. The occluder as recited in claim 18, wherein the occluder is configured to occlude a plurality of collapsible tubes.

35. The occluder as recited in claim 18, wherein the occluder is part of a reusable cycler component of an automated peritoneal dialysis system, and wherein the at least one collapsible tube is fluidically connected to a disposible fluid handling cassette constructed and arranged for operative coupling with the reusable cycler.

19. An occluder for occluding at least one collapsible tube of a medical infusion device, comprising:

a resilient occluding member;

a tube contacting member connected to, or comprising at least a portion of the occluding member;

a force actuator controlled by a microprocessor based control system constructed and positioned to apply a force to bend the occluding member to move the tube contacting member from a tube occluding position to an open position; and

a release member configured and positioned to enable an operator to manually move the tube contacting member from the tube occluding position to the open position even with no force applied to the occluding member by the force actuator.

20. The occluder as recited in claim 19, comprising both a first and a second opposed resilient occluding members.

25. The occluder as recited in claim 20, wherein the occluding members comprise spring plates pivotally connected together at least one of their ends.

26. The occluder as recited in claim 25, wherein the force actuator is constructed and positioned to apply a force sufficient to bend both of the spring plates.

27. The occluder as recited in claim 25, wherein the spring plates are pivotally connected together at opposite first and second ends

28. The occluder as recited in claim 27, wherein the tube contacting member comprises a pinch head connected to the spring plates at the first ends and wherein the second ends of the spring plates are affixed directly or indirectly to a housing to which the occluder is connected.

33. The occluder as recited in claim 20, wherein the release member comprises an elongate release blade pivotally mounted with respect to the occluding members, such that the operator is able to rotate the release blade about a pivot shaft on which it is mounted to force apart the first and second occluding members.

21. An occluder for occluding at least one collapsible tube of a medical infusion device, comprising:

a first and a second opposed occluding members pivotally connected to each other;

a tube contacting member connected to, or comprising at least a portion of, at least one of the first and second occluding members; and

a force actuator constructed and positioned to apply a force to at least one of the first and second occluding members,

wherein upon application of the force by the force actuator, the tube contacting member moves between a tube occluding and an open position.

22. An occluder for occluding at least one collapsible tube of a medical infusion device, comprising:

a first and a second opposed resilient occluding members;

a tube contacting member connected to, or comprising at least a portion of, at least one of the first and second occluding members; and

a single force actuator constructed and positioned to apply a force sufficient to bend both the first and second occluding members,

wherein upon application of the force by the force actuator to bend the first and second occluding members, the tube contacting member moves between a tube occluding and an open position.

23. An occluder for occluding at least one collapsible tube of a medical infusion device, comprising:

a first and a second opposed resilient occluding members defining a space between the occluding members;

a tube contacting member connected to, or comprising at least a portion of, at least one of the first and second occluding members; and

a force actuator constructed and positioned within the space to apply a force to bend at least one of the first and second occluding members,

wherein upon application of the force by the force actuator to bend the occluding member, the tube contacting member moves between a tube occluding and an open position.