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TREATMENT PLANNING FOR ELECTROPORATION-BASED THERAPIES

  • US 20110106221A1
  • Filed: 10/18/2010
  • Published: 05/05/2011
  • Est. Priority Date: 04/29/2008
  • Status: Active Grant
First Claim
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1. A treatment planning system for determining a patient-specific electroporation-based treatment protocol comprising:

  • a processing module operably configured for performing the following stages;

    receiving and processing information from medical images of a target structure and preparing a 3-D reconstruction model of the target structure;

    performing a numerical model analysis using as inputs in the analysis the 3-D reconstruction and information from one or more of physical constraints, tissue heterogeneities, dynamic effects of electropermeabilization, dynamic thermal effects, or effects resulting from multiple treatments; and

    constructing one or more protocols each providing a treatment region with parameters for electroporating the target structure; and

    a processor for executing the stages of the processing module.

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