SATIATION DEVICES AND METHODS

• US 20120016287A1
• Filed: 09/28/2011
• Published: 01/19/2012
• Est. Priority Date: 08/27/2001
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Barosense, Inc. (Boston Scientific Corporation)
• Inventors: Stack, Richard S., Glenn, Richard A., Moody, Trevor J., Silverstein, Fred E., Every, Nathan, Eubanks, William S. Jr.
• Granted Patent: US 8,177,853 B2
• Time in Patent Office: Days
• US Class Current: 604/8
• CPC Class Codes: A61F 2/04 Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts A61F2/18, A61F2/20 take precedence; devices, other than stent-grafts, providing patency to, or preventing collapsing of, tubular structures of the body other than stent-grafts, e.g. stents A61F2/82; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/24 Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
• CPC Class Codes: A61F 2002/044 Oesophagi or esophagi or gullets
• CPC Class Codes: A61F 2002/045 Stomach, intestines
• CPC Class Codes: A61F 2002/067 modular
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61F 5/0069 in the wall of the stomach
• CPC Class Codes: A61F 5/0076 preventing normal digestion, e.g. Bariatric or gastric sleeves
• CPC Class Codes: A61F 5/0079 Pyloric or esophageal obstructions

Abstract

A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.

Claims

1. A method for treating obesity in a subject comprising

intra-orally positioning within the intestine of the subject, an elongate polymeric sleeve at least 20 cm in length and extending between proximal and distal open ends, and

anchoring the sleeve within the duodenum of the intestine, allowing food from the stomach to flow through the tube within the duodenum while preventing absorption of food through the walls of the duodenum.

2. The method of claim 1, wherein the sleeve is anchored within the duodenum with its proximal end adjacent, and at least one centimeter downstream of, the ampulla of vader.

3. The method of claim 1, wherein the sleeve is anchored within the duodenum of the intestine by expanding a self-expanding anchoring mechanism.

4. The method of claim 1, wherein the self-expanding anchoring mechanism is formed of nitinol.

5. The method of claim 1, wherein the sleeve is anchored within the duodenum of the intestine by an anchoring mechanism that includes barbs adapted to engage the walls of the duodenum.