NIRS DEVICE WITH OPTICAL WAVELENGTH AND PATH LENGTH CORRECTION
First Claim
1. A near infrared spectrometer for sensing tissue oxygen measurements in body tissue, comprising:
- a plurality of light sources configured to emit broadband, near infrared measurement light into body tissue;
at least one broadband photodetector configured for sensing at least a portion of the measurement light reflected back from the body tissue;
a means for modeling light attenuations within the body tissue; and
a means for estimating at least one tissue chromophore concentration within the body tissue by comparing attenuations of the sensed measurement light reflected back from the body tissue to the modeled light attenuations.
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Accused Products
Abstract
A near infrared spectrometer and method for wavelength and path length correction are disclosed. The spectrometer includes a number of photodiodes that transmit broadband near infrared measurement light into the tissue and at least one broadband detector which measures the light signal transmitted through the tissue. A processor estimates chromophore concentrations through a comparison of measured light attenuation and modeled light attenuation. The light attenuation model utilizes a light path length distribution derived from a Monte Carlo model and accounts for the spectral shape of the light source as a function of temperature.
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Citations
20 Claims
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1. A near infrared spectrometer for sensing tissue oxygen measurements in body tissue, comprising:
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a plurality of light sources configured to emit broadband, near infrared measurement light into body tissue; at least one broadband photodetector configured for sensing at least a portion of the measurement light reflected back from the body tissue; a means for modeling light attenuations within the body tissue; and a means for estimating at least one tissue chromophore concentration within the body tissue by comparing attenuations of the sensed measurement light reflected back from the body tissue to the modeled light attenuations. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A near infrared spectrometer for sensing tissue oxygen measurements in body tissue, comprising:
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a plurality of light sources configured to emit broadband, near infrared measurement light into body tissue; at least one broadband photodetector configured for sensing at least a portion of the measurement light reflected back from the body tissue; at least one temperature sensor configured for sensing a temperature of the light sources; a light attenuation model configured for modeling light attenuations within the body tissue based at least in part on the temperature sensed by the temperature sensor; a processor configured for estimating at least one tissue chromophore concentration within the body tissue by comparing attenuations of the sensed measurement light reflected back from the body tissue to modeled light attenuations from the light attenuation model; and wherein the processor is configured to sum the attenuations of the light in tissue at a plurality of wavelength increments, the wavelength increments being smaller than a spectral width of each light source and a responsivity of the at least one broadband photodetector.
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16. A method for determining one or more tissue oxygen measurements in body tissue, the method comprising:
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coupling a spectrometer to a tissue of interest, the spectrometer including a plurality of light sources configured to emit broadband, near infrared measurement light into the body tissue and at least one broadband photodetector configured for sensing at least a portion of the measurement light reflected back from the body tissue; measuring the attenuation of the measurement light reflected back from the body tissue; predicting light attenuation within the body tissue using a light attenuation model, wherein the light attenuation model is configured to sum the predicted attenuations of light in tissue at a plurality of wavelength increments, the wavelength increments being smaller than a spectral width of each light source and a responsivity of the at least one broadband photodetector; and estimating at least one tissue chromophore concentration within the body tissue by comparing the attenuation of the measurement light reflected back from the body tissue to the predicted light attenuation. - View Dependent Claims (17, 18, 19, 20)
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Specification