RETAINER ASSEMBLY INCLUDING A TISSUE THICKNESS COMPENSATOR
5 Assignments
0 Petitions
Accused Products
Abstract
A retainer for assembling tissue thickness compensators to a surgical stapler can comprise a grip, a first surface for supporting a first tissue thickness compensator, a second surface for supporting a second tissue thickness compensator, and clips for aligning and attaching the retainer to the surgical stapler. The clips may align and attach the retainer to a staple cartridge of the surgical instrument. The clips may align the retainer with an anvil of the surgical instrument. An insertion tool may be used in combination with the retainer to insert the retainer into the surgical stapler and to push the tissue thickness compensators against the anvil and/or the staple cartridge of the surgical instrument.
528 Citations
32 Claims
-
1-22. -22. (canceled)
-
23. An end effector, comprising:
-
a first jaw; a second jaw, wherein at least one of said first jaw and said second jaw is movable to compress tissue between said first jaw and said second jaw; an implantable arrangement comprising a first layer and a second layer, wherein said first layer and said second layer comprise a polymeric composition; a plurality of first cavities defined in said first layer, wherein said first cavities interconnectedly form a permeable first layer, wherein said first cavities releasably retain a first therapeutic agent, and wherein said first therapeutic agent is configured to induce a first biological response in the tissue; and a plurality of second cavities defined in said second layer, wherein said second cavities interconnectedly form a permeable second layer, wherein said second cavities releasably retain a second therapeutic agent, and wherein said second therapeutic agent is configured to induce a second biological response in the tissue. - View Dependent Claims (24, 25, 26)
-
-
23-1. An end effector, comprising:
-
a first jaw; a second jaw, wherein at least one of said first jaw and said second jaw is movable to compress tissue between said first jaw and said second jaw; an implantable compensator comprising a plurality of layers defining a structural matrix, wherein each of said layers comprises a fibrous weave; a first cavity defined within a first fibrous weave of a first layer of said layers, wherein said first cavity is structured to releasably retain more than one therapeutic agent, and wherein said more than one therapeutic agent are configured to induce at least one biological response in the tissue.
-
-
24-2. The end effector of claim 23, wherein said more than one therapeutic agent comprises at least one hemostatic agent, and wherein the at least one biological response comprises reducing bleeding of the tissue.
-
25-3. The end effector of claim 23, wherein said more than one therapeutic agent comprises at least one anti-inflammatory agent, and wherein the at least one biological response comprises reducing inflammation of the tissue.
-
26-4. The end effector of claim 23, wherein said more than one therapeutic agent comprises at least one antimicrobial agent, and wherein the at least one biological response comprises reducing infection of the tissue.
- 27. The end effector of claim 26, wherein said first therapeutic agent comprises a hemostatic agent, and wherein said first biological response comprises reducing bleeding of the tissue.
-
27-5. An end effector, comprising:
-
a first jaw including a cartridge comprising a plurality of staples; a second jaw including an anvil comprising a plurality of staple forming pockets, wherein at least one of said first jaw and said second jaw is movable to compress tissue between said cartridge and said anvil; a compensator comprising a matrix including a plurality of fibrous layers, wherein said compensator is implantable against the tissue when said staples are ejected from said cartridge to penetrate the tissue and said compensator; a cutting member configured to incise the tissue and said compensator along a cutting line when said compensator is implanted; a cavity defined within a said fibrous layer, wherein said cavity is structured to openly retain at least one therapeutic agent, wherein said cavity is aligned with one of a said staple forming pocket to release said at least one therapeutic agent to treat the penetrated tissue or said cutting line to release said at least one therapeutic agent to treat the incised tissue, and wherein said at least one therapeutic agent is configured to induce at least one biological response in the tissue.
-
-
28-6. The end effector of claim 27, wherein said at least one therapeutic agent comprises a hemostatic agent, and wherein the at least one biological response comprises reducing bleeding of the tissue.
-
29-7. The end effector of claim 27, wherein said at least one therapeutic agent comprises an anti-inflammatory agent, and wherein the at least one biological response comprises reducing inflammation of the tissue.
-
30-8. The end effector of claim 27, wherein said at least one therapeutic agent comprises an antimicrobial agent, and wherein the at least one biological response comprises reducing infection of the tissue.
-
31-9. The end effector of claim 27, wherein each of said plurality of fibrous layers comprises a plurality of cavities, and wherein said layers and said cavities of said matrix are structured to induce tissue and cellular in-growth.
-
32-10. The end effector of claim 31, wherein each of said plurality of fibrous layers comprises fibers configured to induce extracellular matrix secretion.
-
32-11. The end effector of claim 27, wherein said matrix further includes a biocompatible foam comprising a pore morphology arranged to induce tissue in-growth.
Specification