SYSTEM AND METHOD FOR NESTED NEUROSTIMULATION
First Claim
1. A method to deliver nested stimulation to nerve tissue of interest, the method comprising:
- setting first parameters that define a carrier waveform;
setting second parameters that define a high frequency waveform, wherein at least one of the carrier waveform and high frequency waveform are defined to correspond to physiologic neural oscillations associated with the nerve tissue of interest;
operating a pulse generator to generate a nested stimulation waveform that combines the carrier waveform and high frequency waveform, the nested stimulation waveform having a plurality of pulse bursts; and
delivering the nested stimulation waveform through one or more electrodes to the nerve tissue of interest.
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Abstract
A method and system are provided to deliver nested stimulation to brain tissue of interest. The method and system set first parameters that define a carrier waveform. The method and system set second parameters that define a high frequency waveform, wherein at least one of the carrier waveform and high frequency waveform are defined to correspond to physiologic neural oscillations associated with the brain tissue of interest. The method and system operates a pulse generator to generate a nested stimulation waveform that combines the carrier waveform and high frequency waveform. The nested stimulation waveform has a plurality of pulse bursts. The method and system deliver the nested stimulation waveform through one or more electrodes to the brain tissue of interest.
39 Citations
20 Claims
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1. A method to deliver nested stimulation to nerve tissue of interest, the method comprising:
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setting first parameters that define a carrier waveform; setting second parameters that define a high frequency waveform, wherein at least one of the carrier waveform and high frequency waveform are defined to correspond to physiologic neural oscillations associated with the nerve tissue of interest; operating a pulse generator to generate a nested stimulation waveform that combines the carrier waveform and high frequency waveform, the nested stimulation waveform having a plurality of pulse bursts; and delivering the nested stimulation waveform through one or more electrodes to the nerve tissue of interest. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A system to deliver nested stimulation to nerve tissue of interest, the system comprising:
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a lead having an array of stimulation electrodes, the lead configured to be implanted at a target position proximate to nerve tissue of interest; and an implantable medical device (IMD) coupled to the lead, the IMD including a processor and memory storing programmable instructions, the processor executing the programmable instructions to; set first parameters that define a carrier waveform; set second parameters that define a high frequency waveform, wherein at least one of the carrier waveform and high frequency waveform are defined to correspond to physiologic neural oscillations associated with the nerve tissue of interest; operate a pulse generator to generate a nested stimulation waveform that combines the carrier waveform and high frequency waveform, the nested stimulation waveform having a plurality of pulse bursts; and deliver the nested stimulation waveform through one or more electrodes to the nerve tissue of interest. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20)
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Specification