Non-invasive apparatus system for monitoring drug hepatoxicity and uses thereof
First Claim
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1. A non-invasive apparatus system for monitoring drug hepatotoxicity or drug-induced abnormal liver function comprising:
- (a) a sensor for measuring artery blood pressure waveforms to form electric waves representing the artery blood pressure waveforms; and
(b) an analyzer for receiving the electric waves from (a), the electric waves obtained before and after drug intake being calculated by mathematical formulas;
wherein if any altered amounts of any or some of the electric waves are between two certain preset values or higher than a preset value, the analyzer determines that the drug has induced a certain level of liver function change or the drug has induced a severe liver function change; and
then a warning device comprised in the analyzer will emit warning signals.
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Abstract
The invention relates to a non-invasive apparatus system for monitoring drug hepatotoxicity, and its uses in monitoring drug-induced hepatotoxicity and abnormal liver function.
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Citations
18 Claims
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1. A non-invasive apparatus system for monitoring drug hepatotoxicity or drug-induced abnormal liver function comprising:
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(a) a sensor for measuring artery blood pressure waveforms to form electric waves representing the artery blood pressure waveforms; and (b) an analyzer for receiving the electric waves from (a), the electric waves obtained before and after drug intake being calculated by mathematical formulas;
wherein if any altered amounts of any or some of the electric waves are between two certain preset values or higher than a preset value, the analyzer determines that the drug has induced a certain level of liver function change or the drug has induced a severe liver function change; and
then a warning device comprised in the analyzer will emit warning signals. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A non-invasive apparatus system for monitoring drug hepatotoxicity or drug-induced abnormal liver function comprising:
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a wrist type sphygmomanometer which uses a pressure sensory element to transform radial artery blood pressure waveform of a patient'"'"'s arm to electric waves; a bedside recording analyzer which can receive, amplify, filter, and analog-digital transform the electric waves from the sphygmomanometer, wherein the analyzer comprises a small computer to record and analyze the electric waves obtained before and after drug intake by mathematical formulas;
wherein if any altered amounts of any or some of the electric waves are between two certain preset values or higher than a preset value, the drug has induced a certain level of liver function change or the drug has induced a severe liver function change; andan information server and a terminal machine which can send the information from the analyzer to a hospital or clinic for a doctor'"'"'s diagnosis, and send back instructions from the doctor to the patient'"'"'s bedside record analyzer. - View Dependent Claims (16, 17, 18)
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Specification