Amine-derivatives having NPY Y5 receptor antagonistic activity and the uses thereof
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Abstract
This invention provides an anorectic or anti-obesity composition comprising a compound of the formula (I):
- formula (I):
a pharmaceutically acceptable salt or solvate thereof,
wherein
- R1 is optionally substituted lower alkyl,
- Y is —S(O)n- wherein n is 1 or 2, or —CO—,
- R2 is hydrogen or lower alkyl,
- R7 is hydrogen or lower alkyl,
- X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like, and
- Z is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like.
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Citations
12 Claims
- 1. A compound of:
- 2. A pharmaceutical composition, comprising a compound of:
Specification