Methods and devices for controlling biologic microenvironments
First Claim
Patent Images
1. A system for administering therapy to a human body by controlling an environmental parameter of a localized area inside the body, comprising:
- at least one sensor for sensing environmental parameters proximate the localized area;
at least one effector for changing the at least one environmental parameter, implantable proximate the localized area, said at least one environmental parameter including pH;
at least one controller, operatively associated with said at least one sensor, operative to control said at least one effector;
whereby when said at least one effector changes said at least one environmental parameter, the efficacy of the therapy is improved, and wherein the elements of the system are connected to an object placed inside the body, selected from the group consisting of;
endoscope, intramedullary rod, fastener, plate, joint replacement, spinal implant, acetabular replacement, or sheet wrapped around a tubular body structure.
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Accused Products
Abstract
A microenvironment of a biological body is controlled, and more particularly, is measured, changed, and monitored with respect to temperature, pH level, moisture and other tissue parameters of a region of the body while, optionally, administering a therapeutic agent to that region.
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Citations
18 Claims
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1. A system for administering therapy to a human body by controlling an environmental parameter of a localized area inside the body, comprising:
- at least one sensor for sensing environmental parameters proximate the localized area;
at least one effector for changing the at least one environmental parameter, implantable proximate the localized area, said at least one environmental parameter including pH;
at least one controller, operatively associated with said at least one sensor, operative to control said at least one effector;
whereby when said at least one effector changes said at least one environmental parameter, the efficacy of the therapy is improved, and wherein the elements of the system are connected to an object placed inside the body, selected from the group consisting of;
endoscope, intramedullary rod, fastener, plate, joint replacement, spinal implant, acetabular replacement, or sheet wrapped around a tubular body structure. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
- at least one sensor for sensing environmental parameters proximate the localized area;
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17. A system for administering therapy to a human body by controlling an environmental parameter of a localized area inside the body, comprising:
- at least one sensor for sensing environmental parameters proximate the localized area;
at least one effector for changing the at least one environmental parameter, implantable proximate the localized area, said at least one environmental parameter including pH;
at least one controller, operatively associated with said at least one sensor, operative to control said at least one effector;
whereby when said at least one effector changes said at least one environmental parameter, the efficacy of the therapy is improved, and further including a sheet wrapped around a blood vessel, wherein the wrapped sheet constricts a tubular structure decreasing a diameter of same, thereby increasing a rate of blood flow through a constricted space.
- at least one sensor for sensing environmental parameters proximate the localized area;
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18. A system for administering therapy to a human body by controlling an environmental parameter of a localized area inside the body, comprising:
- at least one sensor for sensing environmental parameters proximate the localized area;
at least one effector for changing the at least one environmental parameter, implantable proximate the localized area, said at least one environmental parameter including pH;
at least one controller, operatively associated with said at least one sensor, operative to control said at least one effector;
whereby when said at least one effector changes said at least one environmental parameter, the efficacy of the therapy is improved, wherein said at least one effector includes a suction device operative to create a negative pressure proximate the localized area of the body, whereby the efficacy of the therapy is improved, wherein said suction device is operative to create vasodilation proximate a location where said suction is proximate body tissue, and thereby creates vasoconstriction distal to the location of vasodilation, and wherein said suction device further includes;
means for cooperating with a knee joint including a chamber connected with a first side of the knee joint;
a valve connected with said chamber;
a connector connected to said chamber and a second side of the knee joint;
a tube connected to said chamber, having a distal end extending to the localized area of the body;
whereby movement of the joint produces suction at the distal end of said tube.
- at least one sensor for sensing environmental parameters proximate the localized area;
Specification