System and implantable device for treating chronic kidney disease
First Claim
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1. An implantable dialyzer, comprising:
- a filter pack for hemodialysis and/or ultrafiltration having two or more membranes forming a membrane stack that has alternating dialysate and blood membrane channels interposed between each membrane;
a first manifold assembly connected to a first side of the filter pack containing both a blood and a dialysate manifold, each manifold having a specified cross-sectional geometry, wherein the blood manifold is in fluid communication with the blood membrane channels and the dialysate manifold is in fluid communication with the dialysate membrane channels;
a second manifold assembly connected to a second side of the filter pack containing both a blood and a dialysate manifold, each manifold having a specified cross-sectional geometry, wherein the blood manifold is in fluid communication with the blood membrane channels and the dialysate manifold is in fluid communication with the dialysate membrane channels;
a blood feed-in and a blood feed-out in fluid communication with the blood membrane channels via the blood manifolds;
a dialysate feed-in and a dialysate feed-out in fluid communication with the dialysate membrane channels via the dialysate manifolds; and
a housing encasing the filter pack.
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Abstract
An implantable dialysis device with a related medical system for intracorporeal dialysis and ultrafiltration of blood, and methods of use are described. The medical system includes an extracorporeal module, a cutaneous module, and an implantable module. Features of the implantable module facilitate delivery and flow of blood and dialysate through the medical system. A filter pack within the implantable module performs dialysis and ultrafiltration of blood. System cleansing is also described.
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Citations
36 Claims
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1. An implantable dialyzer, comprising:
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a filter pack for hemodialysis and/or ultrafiltration having two or more membranes forming a membrane stack that has alternating dialysate and blood membrane channels interposed between each membrane; a first manifold assembly connected to a first side of the filter pack containing both a blood and a dialysate manifold, each manifold having a specified cross-sectional geometry, wherein the blood manifold is in fluid communication with the blood membrane channels and the dialysate manifold is in fluid communication with the dialysate membrane channels; a second manifold assembly connected to a second side of the filter pack containing both a blood and a dialysate manifold, each manifold having a specified cross-sectional geometry, wherein the blood manifold is in fluid communication with the blood membrane channels and the dialysate manifold is in fluid communication with the dialysate membrane channels; a blood feed-in and a blood feed-out in fluid communication with the blood membrane channels via the blood manifolds; a dialysate feed-in and a dialysate feed-out in fluid communication with the dialysate membrane channels via the dialysate manifolds; and a housing encasing the filter pack. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35)
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36. An implantable dialyzer, comprising:
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a bundled fiber filter comprising a plurality of hollow fibers for hemodialysis and/or ultrafiltration contained in a dialysate compartment surrounding the hollow fibers; a blood flow distributor that can distribute blood to the hollow fibers using blood from a blood inlet; a blood flow collector that can collect dialyzed blood out from the hollow fibers and exit the dialyzer via a blood outlet; a dialysate inlet that can direct dialysate into the dialysate compartment and a dialysate outlet that can direct dialysate out of the dialysate compartment; and a housing encasing the dialysate compartment.
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Specification