Sample holder with a well having a wicking promoter
First Claim
Patent Images
1. A device for holding a sample, comprising:
- a holder including an upper member attached to a lower member to form a well having a side wall region and a floor, the side wall region extending from a top border to the floor and widening toward the floor at a position intermediate the top border and the floor to create a distinct edge that conceptually divides the well into an upper portion and a lower portion, the well including a side wall protrusion defined by the upper member and adapted to promote wicking of an aqueous sample into the lower portion from the upper portion, the holder defining a channel communicating with the lower portion of the well and with a channel junction that provides a droplet generator;
wherein the side wall protrusion is contiguous with the edge.
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Accused Products
Abstract
Sample holding system, including methods and apparatus, including a holder defining a well having a wicking promoter that encourages flow of a sample to the bottom of the well. Methods of making and using the holder are also disclosed.
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Citations
14 Claims
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1. A device for holding a sample, comprising:
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a holder including an upper member attached to a lower member to form a well having a side wall region and a floor, the side wall region extending from a top border to the floor and widening toward the floor at a position intermediate the top border and the floor to create a distinct edge that conceptually divides the well into an upper portion and a lower portion, the well including a side wall protrusion defined by the upper member and adapted to promote wicking of an aqueous sample into the lower portion from the upper portion, the holder defining a channel communicating with the lower portion of the well and with a channel junction that provides a droplet generator; wherein the side wall protrusion is contiguous with the edge. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A device for holding a sample, comprising:
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a holder including an upper member attached to a lower member to form a well having a side wall region and a floor, the side wall region extending from a top border to the floor and widening toward the floor at a position intermediate the top border and the floor to create a distinct edge that conceptually divides the well into an upper portion and a lower portion, the floor defining a protrusion projecting upwardly in the well, the holder defining a channel communicating with the lower portion of the well; wherein the lower member defines a recess under the protrusion. - View Dependent Claims (8)
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9. A method of making a device for holding a sample, the method comprising:
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providing an upper member defining at least one through-hole bounded by a side wall region, the side wall region extending from a top border to a bottom border and widening toward the bottom border at a position intermediate the top border and the bottom border to create a distinct edge that conceptually divides the through-hole into an upper portion and a lower portion; attaching a lower member to an underside of the upper member to create a well bounded laterally by the side wall region and having a floor formed by the lower member; and deforming the lower member to define a protrusion adapted to promote wicking of an aqueous sample into the lower portion from the upper portion. - View Dependent Claims (10, 11)
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12. A device for holding a sample, comprising:
a holder including an upper member attached to a lower member to form a well having a side wall region and a floor, the side wall region extending from a top border to the floor and widening toward the floor at a position intermediate the top border and the floor to create a distinct edge that conceptually divides the well into an upper portion and a lower portion, the floor defining a protrusion projecting upwardly into the upper portion of the well, the holder defining a channel communicating with the lower portion of the well. - View Dependent Claims (13, 14)
Specification