Sample processing methods
First Claim
1. A sample processing tubule, comprising:
- (a) at least three segments, each of which is;
defined by the tubule;
fluidly isolated, at least in part by a breakable seal;
so expandable as to receive a volume of fluid expelled from another segment; and
so compressible as to contain substantially no fluid when so compressed;
wherein the at least three segments each contains at least one reagent; and
(b) a cap configured to mate with and seal the tubule at a first opening in a first segment of the at least three segments, wherein the cap comprises (i) a substantially hollow cap body extending from a top of the cap body to an orifice at a base of the cap body, and (ii) a cover having a vent hole and positioned on the top of the cap body.
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Accused Products
Abstract
A method of processing a sample may include introducing a sample into a vessel, the vessel having proximal and distal ends, the sample being introduced into the proximal end of the vessel; incubating the sample in the vessel with a substance capable of specific binding to a preselected component of the sample; propelling components of the incubated sample, other than the preselected component, toward the proximal end of the vessel by clamping the vessel distal to the incubated sample and compressing the vessel where the incubated sample is contained; propelling the preselected component toward a distal segment of the vessel by clamping the vessel proximal to the preselected component and compressing the vessel where the preselected component is contained; and mixing the preselected component with a reagent in the distal segment of the vessel.
159 Citations
22 Claims
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1. A sample processing tubule, comprising:
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(a) at least three segments, each of which is;
defined by the tubule;
fluidly isolated, at least in part by a breakable seal;
so expandable as to receive a volume of fluid expelled from another segment; and
so compressible as to contain substantially no fluid when so compressed;
wherein the at least three segments each contains at least one reagent; and(b) a cap configured to mate with and seal the tubule at a first opening in a first segment of the at least three segments, wherein the cap comprises (i) a substantially hollow cap body extending from a top of the cap body to an orifice at a base of the cap body, and (ii) a cover having a vent hole and positioned on the top of the cap body. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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Specification