Multipotent adult stem cells and methods for isolation
First Claim
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1. A method for promoting wound healing in a subject, the method comprising administering isolated expanded human non-embryonic non-germ cells, the cells having undergone at least 10-40 cell doublings in culture, wherein the cells express telomerase and have a normal karyotype, to the subject in a therapeutically effective amount and for a sufficient time to the wound to promote the wound healing in the subject.
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Abstract
The invention provides isolated stem cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple tissue types. Also provided are methods of isolation and culture, as well as therapeutic uses for the isolated cells.
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12 Claims
- 1. A method for promoting wound healing in a subject, the method comprising administering isolated expanded human non-embryonic non-germ cells, the cells having undergone at least 10-40 cell doublings in culture, wherein the cells express telomerase and have a normal karyotype, to the subject in a therapeutically effective amount and for a sufficient time to the wound to promote the wound healing in the subject.
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