Advanced analyte sensor calibration and error detection
First Claim
1. A method for identifying failure of an analyte sensor using a sensor system electronically coupled to the analyte sensor, the method comprising:
- generating a data stream indicative of an analyte concentration of a host by applying a bias voltage to a first analyte sensor at least partially positioned within tissue of the host;
applying a stimulus signal to the first analyte sensor, wherein the stimulus signal is a time-varying signal;
measuring a signal response to the stimulus signal generated by the first analyte sensor;
determining, by the sensor system, that the signal response satisfies one or more predetermined sensor fault criteria associated with membrane damage; and
initiating an error routine via the sensor system in response to determining that the signal response satisfies the one or more predetermined sensor fault criteria.
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Accused Products
Abstract
Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.
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Citations
18 Claims
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1. A method for identifying failure of an analyte sensor using a sensor system electronically coupled to the analyte sensor, the method comprising:
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generating a data stream indicative of an analyte concentration of a host by applying a bias voltage to a first analyte sensor at least partially positioned within tissue of the host; applying a stimulus signal to the first analyte sensor, wherein the stimulus signal is a time-varying signal; measuring a signal response to the stimulus signal generated by the first analyte sensor; determining, by the sensor system, that the signal response satisfies one or more predetermined sensor fault criteria associated with membrane damage; and initiating an error routine via the sensor system in response to determining that the signal response satisfies the one or more predetermined sensor fault criteria. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A system for monitoring an analyte concentration of a host using an analyte sensor, the system configured to also identify failure of the analyte sensor, the system comprising:
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an analyte sensor configured for transcutaneous implantation into a host; and sensor electronics coupled to the analyte sensor, the sensor electronics configured to; generate a data stream indicative of an analyte concentration of the host by applying a bias voltage to the analyte sensor, apply a stimulus signal to the analyte sensor, wherein the stimulus signal is a time-varying signal, measure a signal response to the stimulus signal generated by the first analyte sensor, determine that the signal response satisfies one or more predetermined sensor fault criteria associated with membrane damage, and initiate an error routine in response to determining that the signal response satisfies the one or more predetermined sensor fault criteria. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18)
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Specification