Pharmaceutical compositions based on new anticholinergics and NK1 receptor antagonists
First Claim
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1. ) a pharmaceutical compositions, characterised in that they contain one or more anticholinergics of formula 1
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Abstract
The present invention relates to novel pharmaceutical compositions based on new anticholinergics and NK1 receptor antagonists, processes for preparing them and their use in the treatment of respiratory diseases.
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37 Claims
- 1. ) a pharmaceutical compositions, characterised in that they contain one or more anticholinergics of formula 1
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36. ) A kit comprising:
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(a) a first container containing a first pharmaceutical formulation comprising one or more anticholinergics of formula 1
whereinX—
denotes an anion with a single negative charge, preferably an anion selected from the group consisting of chloride, bromide, iodide, sulphate, phosphate, methanesulphonate, nitrate, maleate, acetate, citrate, fumarate, tartrate, oxalate, succinate, benzoate and p-toluenesulphonate,optionally in the form of the enantiomers, mixtures of the enantiomers or in the form of the racemates thereof, optionally in the form of the solvates or hydrates and optionally together with a pharmaceutically acceptable excipient; and
(b) a second container containing a second pharmaceutical formulation comprising a one or more NK1 receptor antagonists (2), optionally in the form of the enantiomers, mixtures of the enantiomers or in the form of the racemates thereof, optionally in the form of the solvates or hydrates;
each container each optionally further containing a pharmaceutically acceptable excipient.
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37. ) A Method of treatment and/or prevention of a inflammatory or obstructive diseases of the respiratory tract comprising administering to a mammal in need of such a treatment a therapeutically effective amount of the first pharmaceutical formulation (1) comprising one or more anticholinergics of formula 1
Specification