Minimising calibration problems of in vivo glucose sensors
First Claim
1. A method of improving the performance of a glucose oxidase based glucose sensor, said method comprising providing the glucose sensor with a ROS removing compartment capable of reducing the diffusion of ROS out of the glucose sensor to a level at which biointerference is abolished or substantially reduced.
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Abstract
The present invention pertains to the minimisation of calibration problems of glucose sensors. Accordingly, the invention provides a method of improving the performance of a ROS producing glucose sensor, said method comprising providing the glucose sensor with a ROS removing compartment capable of reducing the diffusion of ROS out of the glucose sensor to a level at which biointerference is abolished or substantially reduced. The invention further relates to use of a ROS removing compartment in a ROS producing glucose, a ROS producing glucose sensor comprising a ROS removing compartment, and to the use of such a sensor in a human.
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19 Claims
- 1. A method of improving the performance of a glucose oxidase based glucose sensor, said method comprising providing the glucose sensor with a ROS removing compartment capable of reducing the diffusion of ROS out of the glucose sensor to a level at which biointerference is abolished or substantially reduced.
- 11. Use of a ROS removing compartment in a glucose oxidase based glucose sensor so that biointerference is substantially decreased or avoided.
- 15. A glucose oxidase based glucose sensor comprising a ROS removing compartment capable of reducing the diffusion of ROS out of the glucose sensor to a level at which biointerference is abolished or substantially reduced
Specification