Wireless system for measuring distension in flexible tubes

• US 20040133092A1
• Filed: 07/25/2003
• Published: 07/08/2004
• Est. Priority Date: 03/27/2001
• Status: Abandoned Application

• Current Assignee: BH Research, LLC
• Original Assignee: BH Research, LLC
• Inventors: Kain, Aron Z.
• Application Number:
  US10/470,409
• Publication Number:
  US 20040133092A1
• Time in Patent Office: Days
• US Class Current: 600/377
• CPC Class Codes: A61B 2562/02 Details of sensors specially adapted for in-vivo measurements
• CPC Class Codes: A61B 2562/164 the sensor is mounted in or on a conformable substrate or carrier
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/02108 from analysis of pulse wave characteristics
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/036 by means introduced into body tracts A61B5/032 and A61B5/035 take precedence
• CPC Class Codes: A61B 5/076 Permanent implantations telemetry using implanted circuitry A61B5/0031; implanted stimulators for therapy A61N1/3605, A61N1/362, A61N1/372
• CPC Class Codes: A61B 5/1076 for measuring dimensions inside body cavities, e.g. using catheters A61B3/1005 takes precedence
• CPC Class Codes: A61B 5/6876 Blood vessel
• CPC Class Codes: A61B 5/6884 Clamps or clips
• CPC Class Codes: H01F 17/0006 Printed inductances printed coils for dynamo-electric machines H02K3/26; printed circuits H05K
• CPC Class Codes: H01F 21/04 by relative movement of turns or parts of windings
• CPC Class Codes: H01F 41/045 Trimming
• CPC Class Codes: H01L 27/08 including only semiconductor components of a single kind

Abstract

A wireless sensing system is configured to measure the distension of a flexible tube. The system includes a sensing unit having a sensor element that attaches to the tube and which causes a quiescent frequency produced by the sensing unit to change when the sensor element is physically distorted by distension of the tube. A scanning unit of the system remotely and wirelessly triggers the sensing unit to power up and transmit a modulated signal to the scanning unit for decoding, where the decoded signal indicates a measured quiescent frequency of the sensing unit. The wireless sensing system may be employed, for example, to measure the distension of a blood vessel for the purpose of monitoring blood pressure.

Claims

1. A system for remotely sensing distension or bending in a member, the system comprising a sensor, the sensor comprising:

a sensing element for sensing a measure of distension or bending in the member, wherein at least a portion of the sensor is in physical contact with the member and is sufficiently flexible so that the geometry of the member and distension or bending in the contacted portion of the member remain substantially unaffected by the sensor;

a response circuit for generating a reply signal indicating a measured distention or bending sensed by the sensing element; and

a radiating element for wirelessly transmitting the reply signal.

2. The system of claim 1, wherein the response circuit comprises a transmitter, the transmitter comprising at least one of a voltage controlled oscillator (VCO) and a phase locked loop (PLL).

3. The system of claim 1, wherein the sensor further comprises a receiver for receiving a wireless request signal for sensing.

4. The system of claim 1, wherein the sensor further comprises a power source.

5. The system of claim 3, wherein the receiver further comprises a wake-up circuit for causing the receiver to periodically prepare to receive a request signal.

6. The system of claim 3, wherein the receiver further comprises a decoder for verifying that the request signal is directed to the sensor.

7. The system of claim 6, wherein the receiver verifies the request signal by comparing information in the signal to a unique identifier for the sensor.

8. The system of claim 6, wherein the receiver further comprises a reset timer for resetting the decoder and decoupling power from the sensing element and the transmitter.

9. The system of claim 4, wherein the power source is a battery.

10. The system of claim 4, wherein the power source is a self-generating power source for converting mechanical energy to electrical energy.

11. The system of claim 10, wherein the source of mechanical energy is mechanical motion, and the source of the mechanical motion is associated with one of a group of sources including blood vessels, organs, living beings and industrial devices and machinery.

12. The system of claim 10, wherein the power sources comprises a piezoelectric element.

13. The system of claim 4, wherein the power source is an eternally-supplied radio frequency (RF) signal and wherein the response circuit comprises a resonant transducer in which the sensing element operates as one of a variable capacitor and a variable inductor, the response circuit passively producing the reply signal in response to the externally-supplied RF signal.

14. The system of claim 13, wherein the sensing element further operates as the antenna

15. The system of claim 1, wherein the sensing element signals measures distension or bending as a change in an electrical property of the element, the electrical property being selected from the group consisting of capacitance, inductance, resistance, frequency, phase and amplitude.

16. The system of claim 1, comprising a plurality of sensing elements.

17. The system of claim 16, wherein ones of the plurality of sensing elements are stacked to comprise a multi-element sensor.

18. The system of claim 1, comprising a plurality of sensors, wherein each of the plurality of sensors has a unique identifier.

19. The system of claim 1, further comprising a reference element for calibrating the sensing element.

20. The system of claim 1, wherein the sensor is hermetically sealed in a single package flexibly mounted to the member.

21. The system of claim 20, wherein the package comprises materials suitable for implanting within a biological entity.

22. The system of claim 21, wherein the package materials are selected from the group consisting of gold, titanium, titanium-coated alumina, ceramics, PVC, TFE, polyethylene and KAPTON.

23. The system of claim 1, wherein the sensing element is separately packaged from the other elements of the sensor.

24. The system of claim 1, wherein the member selected from the group consisting of flexible tubes, bending plates, beams and columns.

25. The system of claim 24, wherein the sensing element is configured to be conformally affixed to a surface of a flexible tube.

26. The system of claim 25, wherein the sensing element is configured to be affixed to the tube surface by means of a bioadhesive.

27. The system of claim 25, wherein the sensing element is configured to be sutured to the surface of the tube.

28. The system of claim 25, wherein the sensing element is configured to be affixed to an interior surface of the flexible tube.

29. The system of claim 20, wherein the sensing element is foldable for delivery to the interior of the tube by catheterization.

30. The system of claim 24, wherein the sensing element is configured to be affixed to an exterior surface of the flexible tube.

31. The system of claim 24, wherein the sensing element is affixed to an interior surface of a capsule, the capsule itself being a flexible member and being configured for placement within an interior volume of the flexible tube.

32. The system of claim 31, wherein the capsule comprises a hermetically sealed dielectric material.

33. The system of claim 15, wherein the sensing element comprises a pair of planar electrodes positioned on a flexible substrate.

34. The system of claim 33, wherein the flexible substrate comprises one or more materials that are selected from the group consisting of KAPTON, elastomer, silicone, polyethelene and any other suitable thin, flexible material.

35. The system of claim 33, wherein the sensing element comprises a pair of planar screen electrodes each positioned on an opposing surface of the substrate, such that electrode members in one screen electrode are oriented at an angle with respect to electrode members on the other screen electrode so that fringing fields are formed on the substrate at positions where electrode members of the first electrode and electrode members of the second electrode are non-overlapping.

36. The system of claim 33, wherein each of the pair of planar electrodes of the sensing element has a plurality of fingers and is positioned on a surface of the substrate such that fingers in each of the pluralities are interdigitated, and wherein portions of the substrate between interdigitated fingers are relieved to facilitate movement between the interdigitated fingers.

37. The system of claim 33, wherein the sensing element comprises a surface acoustic wave device comprising a pair of planar electrodes having parallel surfaces positioned on a surface of the substrate at a known distance apart, and further comprising a plurality of planar fingers interposed on the substrate surface at known positions between the electrodes and oriented in parallel with the electrodes.

38. The system of claim 33, wherein the sensing element comprises a pair of planar electrodes each positioned on an opposing surface of the substrate, and one of the pair of electrodes and the substrate are each substantially more compliant than the other electrode.

39. The system of claim 33, wherein each of the pair of electrodes is positioned on an opposing surface of the substrate, a first of the pair of electrodes comprises a ground plane and a second of the pair of electrodes comprises a spiral conductor electrically connected to the ground plane.

40. The system of claim 39, wherein and the substrate is relieved at points intermediate to adjacent portions of the spiral conductor.

41. The system of claim 39, wherein the first of the pair of electrodes comprising a ground plane is a screen electrode.

42. The system of claim 39, wherein the first of the pair of electrodes comprises radial portions radiating from a position adjacent to a center of the second spiral inductor.

43. The system of claim 33, wherein a first of the pair of electrodes comprises a meander line having a length related to a fractional wavelength of an operating frequency for the sensing element and the second of the pair of electrodes comprises a ground plane, the first and second electrodes being positioned on opposing surfaces of the substrate.

44. The system of claim 33, wherein a first of the pair of electrodes is a flexible microstrip electrode having a length related to a fractional wavelength of an operating frequency and the second of the pair of electrodes comprises a ground plane, the first and second electrodes being positioned on opposing surfaces of the substrate.

45. The system of claim 33, wherein a first of the pair of electrodes comprises a comb having tines of a length related to a fractional wavelength of an operating frequency and the second of the pair of electrodes comprises a ground plane, the first and second electrodes being positioned on opposing surfaces of the substrate.

46. The system of claim 3, further comprising a scanner, wherein the scanner comprises:

a transmitter for transmitting the wireless request signal to the sensor;

a receiver for receiving the wireless reply signal from the sensor; and

a processor for decoding the reply signal.

47. The system of claim 46, wherein the scanner further comprises a data storage element for storing the decoded reply.

48. The system of claim 46, wherein the scanner further comprises a display for displaying the decoded reply.

49. The system of claim 46, wherein the scanner further comprises a communications port for exporting the decoded reply.

50. The system of claim 1, wherein the member is a flexible tube for carrying a fluid, and further comprising a second sensing element, wherein the first and second sensing elements are each affixed to one of an inner surface and an outer surface of the flexible tube, each sensing element being positioned at a known distance along a longitudinal axis of the flexible tube.

51. The system of claim 50, wherein the first sensing element produces a measure relating to a change in the radius of the tube, and the second sensing element produces a measure relating to a pressure in the tube.

52. The system of claim 51, wherein the system is configured to measure blood pressure and cardiac stroke volume in a blood vessel.

53. The system of claim 1, wherein the member is a flexible tube for carrying a fluid, and further comprising a second sensor, wherein the first sensor is affixed to one of an inner surface and an outer surface of the flexible tube, and the second sensor overlays the first sensor.

54. The system of claim 1, wherein the member is a flexible tube for carrying at least one of a fluid, gas and solid, the first sensor being affixed to a surface at a closed end of the flexible tube.

55. The system of claim 1, wherein the member is a flexible tube for carrying one of a fluid and a gas, the first sensor being affixed to an inner surface of the tube across a lateral cross section of the tube.

56. A method for measuring distension or bending in a member, the method comprising the steps of:

selecting a sensing element having greater compliance than the member;

conformally affixing the sensing element to a surface of the member; and

measuring an electrical property of the affixed sensing element that varies with distension or bending of the member.

57. The method of claim 56, further comprising the step of electrically coupling the sensing element to a transducer, such that a change in the electrical property of the sensing element causes a change in one of a resonant frequency, amplitude and phase output by the transducer.

58. The method of claim 57, further comprising the step of wirelessly outputting a signal representing said one of a resonant frequency, amplitude and phase output.

59. The method of claim 57, further comprising the steps of:

wirelessly receiving a request signal; and

measuring the electrical property of the sensing element in response to receiving the request signal.

60. The method of claim 59, further comprising the step of validating the request signal before measuring the electrical property.

61. The method of claim 60, wherein the validation step validates the request signal by comparing information in the request signal to a unique identifier.

62. The method of claim 59, further comprising the step of supplying power to the transducer for a predetermined period of time after validating the request signal.

63. The method of claim 58, wherein the output signal contains information relating to a unique indentifier.

64. The method of claim 58, further comprising the steps of:

measuring an electrical property of a reference element;

coupling the reference element to a transducer to produce a resonant frequency output by the transducer; and

wirelessly outputting a signal representing the resonant frequency for the reference element.