Vivo observation device

• US 20050124875A1
• Filed: 09/28/2004
• Published: 06/09/2005
• Est. Priority Date: 10/01/2003
• Status: Abandoned Application

• Current Assignee: Olympus Corporation
• Original Assignee: Olympus Corporation
• Inventors: Kawano, Hironao, Uchiyama, Akio, Takizawa, Hironobu, Kikuchi, Akira
• Application Number:
  US10/952,391
• Publication Number:
  US 20050124875A1
• Time in Patent Office: Days
• US Class Current: 600/407
• CPC Class Codes: A61B 1/00048 Constructional features of the display
• CPC Class Codes: A61B 1/00082 Balloons
• CPC Class Codes: A61B 1/00089 Hoods
• CPC Class Codes: A61B 1/00094 Suction openings
• CPC Class Codes: A61B 1/00096 Optical elements
• CPC Class Codes: A61B 1/00101 the distal tip features being detachable
• CPC Class Codes: A61B 1/00148 using anchoring means
• CPC Class Codes: A61B 1/00158 using magnetic field
• CPC Class Codes: A61B 1/041 Capsule endoscopes for imaging
• CPC Class Codes: A61B 5/073 Intestinal transmitters
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/6885 Monitoring or controlling sensor contact pressure

Abstract

This in vivo observation device is equipped with a capsular casing that is taken orally into the body, and an observation device provided within said casing which observes the inside of the body through an observation wall surface of said casing; and, is provided with a contact auxiliary device that causes the observation wall surface to closely contact to body tissue during observation.

Claims

1. An in vivo observation device comprising:

a capsular casing that is taken orally into the body;

an observation device provided within said casing which observes the inside of the body through an observation wall surface of said casing; and

a contact auxiliary device that causes the observation wall surface to closely contact to body tissue during observation.

2. An in vivo observation device according to claim 1 wherein,

the contact auxiliary device is provided within the casing.

3. An in vivo observation device according to claim 1 wherein,

the contact auxiliary device is an external contact auxiliary device provided with an action generating section that generates an action in the casing from outside the body.

4. An in vivo observation device according to claim 1 wherein,

the contact auxiliary device comprises an external contact auxiliary device provided with an action generating section that generates an action in the casing from outside the body, and a reacting section that receives the action generated by the action generating section provided in the casing.

5. An in vivo observation device according to claim 2 wherein,

the contact auxiliary device has a fluid transfer device installed within the casing which aspirates fluids such as body fluids and gases within the body and causes them to flow from the front of the observation wall surface to the rear, and causes the body tissue to be closely contacted to the observation wall surface as the fluids are aspirated by the fluid transfer device.

6. An in vivo observation device according to claim 5 wherein,

the casing is provided with a cylindrical member that protrudes from the observation wall surface towards the direction of observation.

7. An in vivo observation device according to claim 6 wherein,

the cylindrical member is removable.

8. An in vivo observation device according to claim 5 wherein,

the observation wall surface is provided on the side of the casing.

9. An in vivo observation device according to claim 8 wherein,

a foreign object removal device that protrudes from the outer periphery of the casing is provided around the observation wall surface.

10. An in vivo observation device according to claim 5 wherein,

an outer diameter expansion device is provided on the side of the casing.

11. An in vivo observation device according to claim 2 further comprising:

a capsular casing that is taken orally into the body,

an observation device provided within said casing which observes the inside of the body,

an optically transparent balloon provided on the casing so as to cover the periphery of the observation device and which can be expanded so as to closely contact to the body when moving inside the body, and

an expansion device that expands the balloon by supplying a fluid inside the balloon;

wherein,

the observation device observes the inside of the body through the balloon.

12. An in vivo observation device according to claim 11 wherein,

the expansion device is provided with an acquisition section that acquires body fluid inside the body, and an expansion section that expands the balloon based on the liquid content of the body fluid acquired with the acquisition section.

13. An in vivo observation device according to claim 11 wherein,

a duct that connects the outside and inside of the balloon is provided on the casing, and

the expansion device is provided with a pump that expands the balloon by supplying fluid from the outside to the inside of the balloon through the duct or contacts the balloon by discharging fluid to the outside from inside the balloon, and a control section that controls the operation of said pump.

14. An in vivo observation device according to claim 11 wherein,

another balloon is provided in the casing,

ducts that respectively communicate with the insides of the balloon and the other balloon are provided within the casing, and

the expansion device is provided with a pump that mutually supplies the fluid to both balloons through the ducts, and a control section that controls the operation of said pump.

15. An in vivo observation device according to claim 11 wherein,

the balloon is provided with a reversing prevention device that has projections on the outer surface which protrude towards the rear with respect to the direction of travel.

16. An in vivo observation device according to claim 11 wherein,

the balloon has an electrode on its outer surface, and

an electrical power supply section is provided within the casing that supplies electrical power to the electrode.

17. An in vivo observation device according to claim 11 wherein,

the fluid is an optically transparent liquid drug,

micropores are provided in the balloon that allow the drug to be discharged outside the balloon when the balloon has been expanded at a pressure equal to or greater than a predetermined value, and

the expansion device has a pressure raising device that raises the pressure inside the balloon to the pressure equal to or greater than the predetermined value.

18. An in vivo observation device according to claim 11 wherein,

the fluid is an optically transparent liquid drug, and

a duct that connects the outside and inside of the balloon, a switching valve that can open and close the duct and release drug inside the balloon to the outside, and a switching valve control section that controls operation of the switching valve, are provided in the casing.

19. An in vivo observation device according to claim 11 wherein,

a drug storage section that stores a drug, a duct that connects the drug storage section with the outside of the balloon, a releasing device interposed in the duct which releases drug stored in the drug storage section outside the balloon, and a control section that operates the releasing device, are provided in the casing.

20. An in vivo observation device according to claim 14 wherein,

a releasing device is provided within the balloon that releases the fluid outside the balloon when pressure within the balloon has reached a pressure equal to or greater than a predetermined value,

the fluid is an optically transparent drug, and

the control section operates the pump so that the pressure within the balloon reaches a pressure equal to or greater than a predetermined value.

21. An in vivo observation device according to claim 17 wherein,

another balloon is provided on the casing that has an electrode on its external surface and stores the drug inside,

an electrical power supply section that supplies electrical power to the electrode and ducts that respectively communicate with the insides of the first balloon and the other balloon are provided within the casing, and

the electrical power supply section supplies electrical power to the electrode to release drug.

22. An in vivo observation device according to claim 11 wherein,

the refractive index of the balloon is equal to or lower than the refractive index of the fluid.

23. An in vivo observation device according to claim 2 wherein,

the contact auxiliary device is the difference in specific gravity of the entire device such that the specific gravity of the entire device is set to be larger than the specific gravity of the fluid present in the body.

24. An in vivo observation device according to claim 23 wherein,

the center of gravity is decentered towards the observation wall surface.

25. An in vivo observation device according to claim 3 wherein,

the action generating section is a pressing section that presses against the body, and a grip for operating pressing is provided in the external contact auxiliary device.

26. An in vivo observation device according to claim 25 wherein,

a transmission device that transmits data is provided within the casing, and a display section that displays data transmitted from the transmission device is provided in the pressing section.

27. An in vivo observation device according to claim 25 wherein,

a location detecting device that detects the location of the casing is provided in the external contact auxiliary device.

28. An in vivo observation device according to claim 25 wherein,

a permanent magnet for electromagnetic attraction and an antenna for receiving electrical power are provided within the casing, and a coil for magnetic attraction and an antenna for supplying electrical power are provided in the pressing section.

29. An in vivo observation device according to claim 4 wherein,

the action generating section is a magnetic field generating device, and the reacting section is a permanent magnet or a ferromagnetic body.

30. An in vivo observation device according to claim 29 wherein,

a transmission device that transmits data is provided within the casing, and a display section that displays data transmitted from the transmission device is provided in the pressing section.

31. An in vivo observation device according to claim 29 wherein,

a location detecting device that detects the location of the casing is provided in the external contact auxiliary device.

32. An in vivo observation device according to claim 29 wherein,

a permanent magnet for electromagnetic attraction and an antenna for receiving electrical power are provided within the casing, and a coil for magnetic attraction and an antenna for supplying electrical power are provided in the pressing section.

33. An in vivo observation device according to claim 1 wherein,

a drug administration device is provided that administers a drug at a desired site from the casing when the casing is closely contacted to body tissue.

34. An examination method comprising:

a step in which an in vivo observation device is introduced into a subject,

a step in which the location of the in vivo observation device within the body is recognized,

a step in which the in vivo observation device is closely contacted to a body wall based on the recognized location, and

a step in which an image of the closely contacted section is acquired.

35. An examination method according to claim 34 wherein, the step in which the location within the body is recognized comprises recognizing with an image acquired by the in vivo observation device.

36. An examination method according to claim 34 wherein, the step in which the location within the body is recognized comprises recognizing according to a timer installed in the in vivo observation device.

37. An examination method according to claim 34 wherein, the step in which the location within the body is recognized comprises recognizing based on location information of the in vivo observation device.

38. An examination method according to claim 34 wherein, the step in which the in vivo observation device is closely contacted to a body wall comprises closely contacting by a fluid transfer device that aspirates a fluid such as body fluid or gas in the body from the front in the direction of observation of the in vivo observation device and causes it to flow out to the rear.

39. An examination method according to claim 34 wherein, the step in which the in vivo observation device is closely contacted to a body wall comprises closely contacting a balloon to a body wall by supplying a fluid to an optically transparent balloon provided in the observation section in the in vivo observation device to expand the balloon.

40. An examination method according to claim 34 wherein, the step in which the in vivo observation device is closely contacted to a body wall is a step in which pushing pressure is applied from outside the body to a portion where the in vivo observation device is present from outside the body.

41. An examination method according to claim 34 wherein, the step in which the in vivo observation device is closely contacted to a body wall comprises closely contacting by generating a magnetic field outside the body and attracting a magnet or ferromagnetic body installed within the in vivo observation device.

42. An examination and treatment method comprising:

a step in which an in vivo observation device is introduced into a subject,

a step in which the location within the body is recognized,

a step in which the in vivo observation device is closely contacted to a body wall based on the recognized location,

a step in which an image of the closely contacted section is acquired,

a step in which the acquired image is confirmed, and

a step in which a drug is released if necessary.

43. An examination and treatment method according to claim 42 wherein, the step in which the location within the body is recognized comprises recognizing with an image acquired by the in vivo observation device.

44. An examination and treatment method according to claim 42 wherein, the step in which the location within the body is recognized comprises recognizing according to a timer installed in the in vivo observation device.

45. An examination and treatment method according to claim 42 wherein, the step in which the location within the body is recognized comprises recognizing based on location information of the in vivo observation device.

46. An examination and treatment method according to claim 42 wherein, the step in which the in vivo observation device is closely contacted to a body wall comprises closely contacting by a fluid transfer device that aspirates a fluid such as body fluid or gas in the body from the front in the direction of observation of the in vivo observation device and causes it to flow out to the rear.

47. An examination and treatment method according to claim 42 wherein, the step in which the in vivo observation device is closely contacted to a body wall comprises closely contacting a balloon to a body wall by supplying a fluid to an optically transparent balloon provided in the observation section in the in vivo observation device to expand the balloon.

48. An examination and treatment method according to claim 42 wherein, the step in which the in vivo observation device is closely contacted to a body wall is a step in which pushing pressure is applied from outside the body to a portion where the in vivo observation device is present.

49. An examination and treatment method according to claim 42 wherein, the step in which the in vivo observation device is closely contacted to a body wall comprises closely contacting by generating a magnetic field outside the body and attracting a magnet or ferromagnetic body installed within the in vivo observation device.