Sensor for measuring a bioanalyte such as lactate

• US 20050238537A1
• Filed: 12/01/2004
• Published: 10/27/2005
• Est. Priority Date: 10/07/1999
• Status: Abandoned Application

• Current Assignee: Pepex Biomedical, LLC
• Original Assignee: Pepex Biomedical, LLC
• Inventors: Tomasco, Michael F., Say, James L., Sakslund, Henning
• Application Number:
  US11/002,718
• Publication Number:
  US 20050238537A1
• Time in Patent Office: Days
• US Class Current: 422/82.20
• CPC Class Codes: A61B 17/02 for holding wounds open; Tractors specula A61B1/32 ; drainage appliances for wounds A61M27/00
• CPC Class Codes: C12Q 1/004 mediator-assisted
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: G01N 33/49 Blood chemical methods for determining blood cell populations G01N33/5094; chemical analysis of blood groups or blood types G01N33/80

Abstract

The present disclosure relates to a sensor including a plurality of electrically conductive fibers. The sensor also includes a sensing material coating at least some of the fibers, and an insulating layer that surrounds the electrically conductive fibers.

Claims

1. A sensor comprising:

a plurality of electrically conductive fibers;

a sensing material coating at least some of the fibers; and

an insulating layer positioned about the plurality of electrically conductive fibers;

wherein the insulating layer forms an analyte barrier that surrounds the conductive fibers, the analyte barrier defining a plurality of openings for allowing an analyte to access the sensing material.

4. The sensor of claim 1, wherein the insulating layer comprises an electrical insulator.

5. The sensor of claim 1, wherein the insulating layer comprises polyurethane.

6. The sensor of claim 1, wherein the conductive fibers comprise carbon.

7. The sensor of claim 1, wherein the sensing material includes a redox compound.

8. The sensor of claim 7, wherein the redox compound comprises a transition metal complex with one or more organic ligands.

9. The sensor of claim 7, wherein the sensing material includes a redox enzyme.

10. The sensor of claim 9, wherein the redox enzyme catalyzes the oxidation or reduction of an analyte.

11. The sensor of claim 10, wherein the analyte comprises lactate.

12. The sensor of claim 11, wherein the redox enzyme is selected from the group of lactate oxidase and lactate dehydrogenase.

13. The sensor of claim 10, wherein the analyte comprises glucose.

14. The sensor of claim 13, wherein the redox enzyme is selected from the group of glucose oxidase and glucose dehydrogenase.

15. The sensor of claim 1, wherein the fibers form a sheet.

16. The sensor of claim 1, wherein the fibers are interwoven.

17. The sensor of claim 1, wherein the fibers form a piece of fabric.

2. (canceled)

3. (canceled)

18. (canceled)

19. A retractor device comprising:

a surgical retractor blade; and

a lactate sensor positioned adjacent to the retractor blade for sensing lactate levels in tissue being compressed by the retractor blade, the lactate sensor including;

a plurality of electrically conductive fibers;

a sensing material coating at least some of the fibers, the sensing material including a redox compound for oxidizing or reducing lactate; and

an insulating layer positioned about the plurality of electrically conductive fibers.

20. The retractor of claim 19, wherein the lactate sensor engages a surgical pad.

21. The retractor of claim 19, wherein the insulating layer defines a plurality of openings for allowing blood to access the sensing material on the fibers.

22. The retractor of claim 19, wherein the sensing material includes a redox enzyme that catalyzes the oxidation or reduction of lactate.

23. The retractor of claim 20, wherein the lactate sensor is positioned adjacent to a surgical pad.

24. A sensor comprising:

a plurality of electrically conductive fibers;

a sensing material coating at least some of the fibers; and

an insulating layer positioned about the plurality of electrically conductive fibers;

wherein the insulating layer forms an analyte barrier that surrounds the conductive fibers, the insulating layer defining at least one transversely formed opening for allowing an analyte to access the sensing material.