Apparatus and method for transdermal delivery of desmopressin
First Claim
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1. A delivery system for transdermally delivering desmopressin to a patient, comprising:
- a microprojection member having a plurality of microprojections that are adapted to pierce the stratum corneum of the patient; and
a biocompatible coating disposed on said microprojection member, said coating being formed from a coating formulation having desmopressin disposed therein.
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Abstract
An apparatus and method for transdermally delivering desmopressin comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In one embodiment, the desmopressin is contained in a biocompatible coating that is applied to the microprojection member.
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33 Claims
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1. A delivery system for transdermally delivering desmopressin to a patient, comprising:
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a microprojection member having a plurality of microprojections that are adapted to pierce the stratum corneum of the patient; and
a biocompatible coating disposed on said microprojection member, said coating being formed from a coating formulation having desmopressin disposed therein. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 28, 30, 32)
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21. A method of transdermally delivering desmopressin to a patient, comprising the steps of:
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providing a microprojection member having a plurality of microprojections, said microprojection member having a coating disposed thereon, said coating including desmopressin;
applying said microprojection member to a skin site of said patient, whereby said plurality of microprojections pierce the stratum corneum and deliver said desmopressin to said patient; and
removing said microprojection member from said skin site. - View Dependent Claims (22, 23, 24, 25, 26, 27, 29, 31, 33)
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Specification