Analyte sensing biointerface
First Claim
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1. A sensor for measuring an analyte in a host, the sensor comprising a biointerface comprising a porous biocompatible matrix, wherein electroactive surfaces are distributed within at least some pores in the biointerface.
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Abstract
Disclosed herein is an analyte sensing biointerface that comprises a sensing electrode incorporated within a non-conductive matrix comprising a plurality of passageways extending through the matrix to the sensing electrode. Also disclosed herein are methods of manufacturing a sensing biointerface and methods of detecting an analyte within tissue of a host using an analyte sensing biointerface.
132 Citations
18 Claims
- 1. A sensor for measuring an analyte in a host, the sensor comprising a biointerface comprising a porous biocompatible matrix, wherein electroactive surfaces are distributed within at least some pores in the biointerface.
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18. An implantable analyte sensor, comprising:
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a porous biocompatible matrix; and
electroactive surfaces incorporated into the biocompatible matrix in such a way so that the electroactive surfaces and biocompatible matrix manage a foreign body response to resist barrier cell formation and allow transport of analytes to the electroactive surfaces when the sensor is implanted into a body.
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Specification