Method for purifying succinic acid from fermentation broth

• US 20060276674A1
• Filed: 03/29/2006
• Published: 12/07/2006
• Est. Priority Date: 09/30/2003
• Status: Abandoned Application

• Current Assignee: Ajinomoto Co., Inc., Mitsubishi Chemical Corporation (Mitsubishi Chemical Group Corp.)
• Original Assignee: Ajinomoto Co., Inc., Mitsubishi Chemical Corporation (Mitsubishi Chemical Group Corp.)
• Inventors: Fujiwara, Kenji, Sano, Chiaki, Satou, Takeru, Kushiku, Takeshi
• Application Number:
  US11/391,327
• Publication Number:
  US 20060276674A1
• Time in Patent Office: Days
• US Class Current: 562/562
• CPC Class Codes: C07C 51/47 by solid-liquid treatment; by chemisorption
• CPC Class Codes: C07C 55/10 Succinic acid
• CPC Class Codes: C12P 7/46 Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid

Abstract

Succinic acid is produced by bringing a succinic acid-containing liquid containing succinic acid and cation which is obtained by fermentation or an enzymatic method into contact with an H-type strongly acidic cation-exchange resin in an amount equivalent to or more than the amount of cation other than hydrogen ion contained in the succinic acid-containing liquid, and precipitating a crystal of succinic acid from the obtained ion-exchange-treated liquid to obtain purified succinic acid.

Claims

1. A method for purifying succinic acid from a succinic acid-containing liquid containing cation which is obtained by fermentation or an enzymatic method, which comprises bringing the succinic acid-containing liquid into contact with an H-type strongly acidic cation-exchange resin in an amount equivalent to or more than the amount of cation other than hydrogen ion contained in the succinic acid-containing liquid, and precipitating a crystal of succinic acid from the obtained ion-exchange-treated liquid to obtain purified succinic acid.

2. The method according to claim 1, wherein the succinic acid-containing liquid contains a salt of succinic acid.

3. The method according to claim 2, wherein the salt of succinic acid is selected from sodium succinate, potassium succinate, magnesium succinate, calcium succinate and ammonium succinate.

4. The method according to claim 3, wherein the succinic acid-containing liquid contains a salt of carbonic acid, and the succinic acid-containing liquid is added with an acid to be adjusted to pH 5.0 or lower, and then brought into contact with the H-type strongly acidic cation-exchange resin.

5. The method according to claim 4, wherein the ion-exchange-treated liquid is used as the acid.

6. The method according to claim 4, wherein the ion-exchange-treated liquid from which the precipitated succinic acid has been removed is used as the acid.

7. A method for producing succinic acid, which comprises allowing bacterial cells or treated bacterial cells to act on an organic raw material in an aqueous reaction solution to obtain a succinic acid-containing liquid, bringing the succinic acid-containing liquid into contact with an H-type strongly acidic cation-exchange resin in an amount equivalent to or more than the amount of cation other than hydrogen ion contained in the succinic acid-containing liquid, and precipitating a crystal of succinic acid from the obtained ion-exchange-treated liquid to obtain purified succinic acid.

8. The method according to claim 7, wherein the aqueous reaction solution is neutralized with magnesium carbonate or magnesium hydroxide.