Dynamic reinforcement of the lower esophageal sphincter

• US 20060276812A1
• Filed: 04/03/2006
• Published: 12/07/2006
• Est. Priority Date: 04/04/2005
• Status: Abandoned Application

• Current Assignee: MiCardia Corporation
• Original Assignee: MiCardia Corporation
• Inventors: Hill, James W., Moaddeb, Shawn
• Application Number:
  US11/396,500
• Publication Number:
  US 20060276812A1
• Time in Patent Office: Days
• US Class Current: 606/157
• CPC Class Codes: A61B 17/1322 comprising a flexible encircling member A61B17/135 takes precedence
• CPC Class Codes: A61F 2/0036 implantable A61F2/0018 takes precedence
• CPC Class Codes: A61F 2002/044 Oesophagi or esophagi or gullets
• CPC Class Codes: A61F 2250/0001 Means for transferring electromagnetic energy to implants
• CPC Class Codes: A61F 5/0079 Pyloric or esophageal obstructions

Abstract

Gastroesophageal implants are implantable at or near the gastroesophageal junction in order reinforce the lower esophageal sphincter and prevent gastric reflux. In a contracted configuration, the implants prevent or substantially restrict communication between the stomach and the esophagus. In an open configuration, the implants do not substantially restrict communication between the stomach and the esophagus. Certain embodiments of the implants are capable of detecting various conditions of the esophagus and/or stomach and moving between the contracted and open configurations in response to the detected condition(s).

Claims

1. An implant configured to encompass, at least partially, a portion of a person'"'"'s gastrointestinal tract at or near the gastroesophageal junction thereof, the implant comprising:

an implant body;

a sensor configured to detect a condition of the person'"'"'s esophagus; and

an actuator coupled to the implant body and in communication with the sensor;

wherein the implant is configured to change from a contracted configuration, in which the implant at least partially constricts the gastrointestinal tract at or near the gastroesophageal junction, to an open configuration, in which the implant does not substantially constrict the gastrointestinal tract; and

wherein the actuator is configured to apply force to the implant body in changing the implant from the open configuration to the contracted configuration, and/or from the contracted configuration to the open configuration, in response to the condition of the esophagus detected by the sensor.

2. The implant of claim 1, wherein the actuator is configured to apply a force to the body to cause the body to move from the contracted configuration to the open configuration.

3. The implant of claim 1, wherein the actuator is configured to apply a force to the body to cause the body to move from the open configuration to the contracted configuration.

4. The implant of claim 1, wherein the condition of the person'"'"'s esophagus comprises at least one characteristic of an electrical signal emanating from the esophagus.

5. The implant of claim 1, wherein the condition of the person'"'"'s esophagus comprises a pressure and/or at least one characteristic of a pressure wave detected from the esophagus.

6. The implant of claim 1, wherein the actuator comprises a motor.

7. The implant of claim 6, wherein the actuator further comprises a linear translator.

8. The implant of claim 6, wherein the actuator further comprises a power source.

9. The implant of claim 1, further comprising a processor in electrical communication with the sensor.

10. The implant of claim 9, wherein the processor is configured to receive an input signal from the sensor and to produce an output signal to be transmitted to the actuator.

11. The implant of claim 1, wherein the actuator is at least partially contained within the implant body.

12. The implant of claim 1, wherein the sensor is configured to measure a frequency pattern and/or an amplitude pattern of peristaltic waves.

13. The implant of claim 1, wherein the sensor comprises a pressure sensor, or a strain gauge, or an electrode.

14. An implant configured to encompass, at least partially, a portion of a human esophagus at or near a lower esophageal sphincter thereof, the implant comprising:

an implant body; and

means for moving the body between a contracted configuration, in which the implant constricts the gastrointestinal tract at or near the gastroesophageal junction, and an open configuration, in which the implant does not substantially constrict the gastrointestinal tract.

15. The implant of claim 14, further comprising means for sensing a condition of the person'"'"'s esophagus, the means for sensing being in communication with the means for moving.

16. The implant of claim 14, wherein the means for moving the body comprises a motor and a linear translator.

17. A method of reinforcing a lower esophageal sphincter of a patient'"'"'s esophagus, the method comprising the steps of:

securing an implant at or near the lower esophageal sphincter, such that the implant at least partially encompasses a portion of the patient'"'"'s gastrointestinal tract at or near the gastroesophageal junction, and at least partially constricts the gastrointestinal tract;

allowing the implant to sense a condition of the esophagus; and

allowing the implant to open in response to the sensed condition such that the implant does not substantially constrict the gastrointestinal tract at or near the gastroesophageal junction.

18. The method of claim 17, further comprising the step of allowing the implant to constrict the gastrointestinal tract after a predetermined interval.

19. The method of claim 17, further comprising allowing the implant to constrict the gastrointestinal tract automatically in response to a further sensed condition of the esophagus.