Signal processing for measurement of physiological analytes
First Claim
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1. A method of converting post-calibration data to provide a measurement of analyte amount or concentration in a subject, said method comprising:
- obtaining a raw signal from the analyte, wherein (i) interstial fluid of the subject comprises said analyte, (ii) obtaining said raw signal comprises contacting said interstitial fluid with a sensing device, and (iii) said raw signal is related to analyte amount or concentration in the biological system;
subjecting the raw signal to at least one conversion step in order to convert said raw signal to an initial signal output which is indicative of the amount or concentration of analyte;
calibrating the sensing device by performing at least one calibration step that converts the initial signal output to a measurement value indicative of the amount or concentration of analyte present in the biological system; and
converting a raw signal or initial signal output obtained after the calibration of the sensing device to a measurement value indicative of the amount or concentration of analyte present in the subject.
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Abstract
A method is provided for continually or continuously measuring the concentration of target chemical analytes present in a biological system, and processing analyte-specific signals to obtain a measurement value that is closely correlated with the concentration of the target chemical analyte in the biological system. One important application of the invention involves a method for signal processing in a system for monitoring blood glucose values.
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15 Claims
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1. A method of converting post-calibration data to provide a measurement of analyte amount or concentration in a subject, said method comprising:
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obtaining a raw signal from the analyte, wherein (i) interstial fluid of the subject comprises said analyte, (ii) obtaining said raw signal comprises contacting said interstitial fluid with a sensing device, and (iii) said raw signal is related to analyte amount or concentration in the biological system;
subjecting the raw signal to at least one conversion step in order to convert said raw signal to an initial signal output which is indicative of the amount or concentration of analyte;
calibrating the sensing device by performing at least one calibration step that converts the initial signal output to a measurement value indicative of the amount or concentration of analyte present in the biological system; and
converting a raw signal or initial signal output obtained after the calibration of the sensing device to a measurement value indicative of the amount or concentration of analyte present in the subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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Specification