Tissue augmentation methods using a medical injection apparatus
First Claim
1. A method for placing an injectable therapeutic filler material to a targeted treatment location comprising:
- inserting an injection apparatus wherein, said injection apparatus comprises a transition-bore needle apparatus, which comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, wherein a diameter of the proximal end of the transition-bore needle apparatus is greater than a diameter of the distal end of the transition-bore needle apparatus, wherein a proximal portion of the transition-bore needle apparatus comprises a first needle having a first diameter, and a distal portion of the transition-bore needle apparatus comprises a second needle having a second diameter, and wherein the proximal end of the first needle defines a surface that is nonperpendicularly oriented to the lumen of the transition-bore needle apparatus; and
, a surgical device suitable for insertion within a body lumen;
and, delivering said injectable therapeutic filler material through said injection apparatus to said targeted treatment location.
4 Assignments
0 Petitions
Accused Products
Abstract
An injection apparatus that includes components that facilitate injection of relatively viscous materials into a subject is provided as well as methods of use. An injection apparatus may include a transition-bore needle apparatus, which has a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, in which the diameter of the proximal end is greater than the diameter of the distal end. An injection apparatus may include a hand-held injection facilitation apparatus, which may be coupled to a syringe. The hand-held injection facilitation apparatus can include a pivot arm and a body with a rod disposed within the body and coupled to the pivot arm. Movement of the pivot arm results in a proximal or distal movement of the rod within the body to effectively cause material to be expelled from the syringe. An injection apparatus may include a transition-bore needle apparatus and a hand-held injection facilitation apparatus in combination.
261 Citations
120 Claims
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1. A method for placing an injectable therapeutic filler material to a targeted treatment location comprising:
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inserting an injection apparatus wherein, said injection apparatus comprises a transition-bore needle apparatus, which comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, wherein a diameter of the proximal end of the transition-bore needle apparatus is greater than a diameter of the distal end of the transition-bore needle apparatus, wherein a proximal portion of the transition-bore needle apparatus comprises a first needle having a first diameter, and a distal portion of the transition-bore needle apparatus comprises a second needle having a second diameter, and wherein the proximal end of the first needle defines a surface that is nonperpendicularly oriented to the lumen of the transition-bore needle apparatus; and
,a surgical device suitable for insertion within a body lumen;
and, delivering said injectable therapeutic filler material through said injection apparatus to said targeted treatment location. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 120)
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40. A method for treating gastro-esophogeal reflux disease comprising:
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inserting an injection apparatus into the esophagus of said subject, said injection apparatus comprising a transition-bore needle apparatus, which comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, wherein a diameter of the proximal end of the transition-bore needle apparatus is greater than a diameter of the distal end of the transition-bore needle apparatus, wherein a proximal portion of the transition-bore needle apparatus comprises a first needle having a first diameter, and a distal portion of the transition-bore needle apparatus comprises a second needle having a second diameter, and wherein the proximal end of the first needle defines a surface that is nonperpendicularly oriented to the lumen of the transition-bore needle apparatus; and
,a gastroscope;
and, delivering an injectable therapeutic filler material through said injection apparatus around the lower esophageal sphincter to alter the biomechanical characteristics of said sphincter surrounding tissues to alleviate gastro-esophageal reflux. - View Dependent Claims (41, 42, 43, 44, 45, 46)
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47. A method for treating stress urinary incontinence comprising:
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inserting an injection apparatus into the urethra of said subject, said injection apparatus comprising a transition-bore needle apparatus, which comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, wherein a diameter of the proximal end of the transition-bore needle apparatus is greater than a diameter of the distal end of the transition-bore needle apparatus, wherein a proximal portion of the transition-bore needle apparatus comprises a first needle having a first diameter, and a distal portion of the transition-bore needle apparatus comprises a second needle having a second diameter, and wherein the proximal end of the first needle defines a surface that is nonperpendicularly oriented to the lumen of the transition-bore needle apparatus; and
,a cytoscope;
and, delivering a therapeutic filler material through said injection apparatus around the urinary sphincter to alter the biomechanical characteristics of said sphincter surrounding tissues to alleviate stress urinary incontinence. - View Dependent Claims (48, 49, 50, 51, 52, 53)
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54. A method for enabling contraception comprising:
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inserting an injection apparatus into the fallopian tube of a subject, said injection apparatus comprising a transition-bore needle apparatus, which comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, wherein a diameter of the proximal end of the transition-bore needle apparatus is greater than a diameter of the distal end of the transition-bore needle apparatus, wherein a proximal portion of the transition-bore needle apparatus comprises a first needle having a first diameter, and a distal portion of the transition-bore needle apparatus comprises a second needle having a second diameter, and wherein the proximal end of the first needle defines a surface that is nonperpendicularly oriented to the lumen of the transition-bore needle apparatus; and
,a laproscope;
and, delivering an injectable therapeutic filler material through said injection apparatus into said fallopian tube to provide a barrier and prevent fertilization. - View Dependent Claims (55, 56, 57, 58, 59, 60)
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61. A method for enabling contraception comprising:
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inserting an injection apparatus into the vas deferens of a subject, said injection apparatus comprising a transition-bore needle apparatus, which comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, wherein a diameter of the proximal end of the transition-bore needle apparatus is greater than a diameter of the distal end of the transition-bore needle apparatus, wherein a proximal portion of the transition-bore needle apparatus comprises a first needle having a first diameter, and a distal portion of the transition-bore needle apparatus comprises a second needle having a second diameter, and wherein the proximal end of the first needle defines a surface that is nonperpendicularly oriented to the lumen of the transition-bore needle apparatus; and
,an angioscope;
and, delivering an injectable therapeutic filler material through said injection apparatus into said vas deferns to provide a barrier and prevent sperm from entering the ejaculatory duct. - View Dependent Claims (62, 63, 64, 65, 66, 67)
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68. A method for treating bladder incontinence comprising:
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inserting an injection apparatus into the bladder of said subject, said injection apparatus comprising a transition-bore needle apparatus, which comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, wherein a diameter of the proximal end of the transition-bore needle apparatus is greater than a diameter of the distal end of the transition-bore needle apparatus, wherein a proximal portion of the transition-bore needle apparatus comprises a first needle having a first diameter, and a distal portion of the transition-bore needle apparatus comprises a second needle having a second diameter, and wherein the proximal end of the first needle defines a surface that is nonperpendicularly oriented to the lumen of the transition-bore needle apparatus; and
,a cytoscope;
and, delivering an injectable therapeutic filler material through said injection apparatus around the bladder sphincter to alter the biomechanical characteristics of said sphincter surrounding tissues to alleviate bladder incontinence. - View Dependent Claims (69, 70, 71, 72, 73, 74)
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75. A method for treating fecal incontinence comprising:
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inserting an injection apparatus into the rectum of said subject, said injection apparatus comprising a transition-bore needle apparatus, which comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, wherein a diameter of the proximal end of the transition-bore needle apparatus is greater than a diameter of the distal end of the transition-bore needle apparatus, wherein a proximal portion of the transition-bore needle apparatus comprises a first needle having a first diameter, and a distal portion of the transition-bore needle apparatus comprises a second needle having a second diameter, and wherein the proximal end of the first needle defines a surface that is nonperpendicularly oriented to the lumen of the transition-bore needle apparatus; and
,a proctoscope;
and, delivering an injectable therapeutic filler material through said injection apparatus around the anal sphincter to alter the biomechanical characteristics of said sphincter surrounding tissues to alleviate fecal incontinence. - View Dependent Claims (76, 77, 78, 79, 80, 81)
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82. A method for treating obesity comprising:
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inserting an injection apparatus into the stomach of said subject, said injection apparatus comprising a transition-bore needle apparatus, which comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, wherein a diameter of the proximal end of the transition-bore needle apparatus is greater than a diameter of the distal end of the transition-bore needle apparatus, wherein a proximal portion of the transition-bore needle apparatus comprises a first needle having a first diameter, and a distal portion of the transition-bore needle apparatus comprises a second needle having a second diameter, and wherein the proximal end of the first needle defines a surface that is nonperpendicularly oriented to the lumen of the transition-bore needle apparatus; and
,a gastroscope;
and, delivering an injectable therapeutic filler material through said injection apparatus around the pyloric sphincter to alter the biomechanical characteristics of said sphincter surrounding tissues to restrict gastric emptying. - View Dependent Claims (83, 84, 85, 86, 87, 88)
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89. A method for treating joint cartilage damage comprising:
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inserting an injection apparatus into the damaged joint of said subject, said injection apparatus comprising a transition-bore needle apparatus, which comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, wherein a diameter of the proximal end of the transition-bore needle apparatus is greater than a diameter of the distal end of the transition-bore needle apparatus, wherein a proximal portion of the transition-bore needle apparatus comprises a first needle having a first diameter, and a distal portion of the transition-bore needle apparatus comprises a second needle having a second diameter, and wherein the proximal end of the first needle defines a surface that is nonperpendicularly oriented to the lumen of the transition-bore needle apparatus; and
,an arthroscope;
and, delivering an injectable therapeutic filler material through said injection apparatus into the joint to alter the biomechanical characteristics of said joint cartilage surrounding tissues to alleviate joint damage. - View Dependent Claims (90, 91, 92, 93, 94, 95)
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96. A method for embolotherapy comprising:
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inserting an injection apparatus into the blood vessel of said subject, said injection apparatus comprising a transition-bore needle apparatus, which comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, wherein a diameter of the proximal end of the transition-bore needle apparatus is greater than a diameter of the distal end of the transition-bore needle apparatus, wherein a proximal portion of the transition-bore needle apparatus comprises a first needle having a first diameter, and a distal portion of the transition-bore needle apparatus comprises a second needle having a second diameter, and wherein the proximal end of the first needle defines a surface that is nonperpendicularly oriented to the lumen of the transition-bore needle apparatus; and
,an angioscope;
and, delivering an injectable therapeutic filler material through said injection apparatus into said blood vessel to interrupt or diminish blood flow. - View Dependent Claims (97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112)
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113. A method for treating spinal disc injury comprising:
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inserting an injection apparatus into the nucleus pulposus, or space vacated from the removal thereof, of said subject, said injection apparatus comprising a transition-bore needle apparatus, which comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, wherein a diameter of the proximal end of the transition-bore needle apparatus is greater than a diameter of the distal end of the transition-bore needle apparatus, wherein a proximal portion of the transition-bore needle apparatus comprises a first needle having a first diameter, and a distal portion of the transition-bore needle apparatus comprises a second needle having a second diameter, and wherein the proximal end of the first needle defines a surface that is nonperpendicularly oriented to the lumen of the transition-bore needle apparatus; and
,endoscopic discectomy equipment;
and, delivering an injectable therapeutic filler material through said injection apparatus into the nucleus pulposus, or space vacated from the removal thereof, to restore the biomechanical characteristics of said spinal surrounding tissues. - View Dependent Claims (114, 115, 116, 117, 118, 119)
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Specification