Signal transmitter and control circuit for a physiological variable

• US 20070123760A1
• Filed: 11/15/2006
• Published: 05/31/2007
• Est. Priority Date: 11/15/2005
• Status: Abandoned Application

• Current Assignee: Bernd Scholler, Elmar Vitt, Klaus Forstner, Thomas Magin, Thomas Marx
• Original Assignee: Bernd Scholler, Elmar Vitt, Klaus Forstner, Thomas Magin, Thomas Marx
• Inventors: Marx, Thomas, Vitt, Elmar, Magin, Thomas, Forstner, Klaus, Scholler, Bernd
• Application Number:
  US11/600,333
• Publication Number:
  US 20070123760A1
• Time in Patent Office: Days
• US Class Current: 600/310
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7207 of noise induced by motion artifacts
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 1/3609 Physical characteristics of the blood, e.g. haematocrit, urea
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 2230/04 Heartbeat characteristics, e.g. ECG, blood pressure modulation
• CPC Class Codes: A61M 2230/204 partial carbon monoxide pressure (P-CO)
• CPC Class Codes: A61M 2230/205 partial oxygen pressure (P-O2)
• CPC Class Codes: A61M 2230/207 hematocrit
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

For detecting and processing a physiological variable, a signal transmitter has devices for processing, using, and/or providing signals, which are generated from measurement values of the physiological variable. In accordance with a sequence control approach, the measurement values are acquired from the detection of electromagnetic waves of different wavelengths. Before the signals are detected, the electromagnetic waves pass through the medium to be examined or are reflected by this medium. For at least a certain percentage of the overall signal quantity, at least two measurement values detected close together in time are used for each generated signal. The signal transmitter is suitable for use in a control circuit, which is designed with an actuator to influence the physiological variable detected instrumentally by the signal transmitter.

Claims

1. A signal transmitter comprising a device for processing, using, and/or providing signals which are generated from measurement values of a physiological variable, wherein

a sequence control approach is implemented in such a way that the measurement values are acquired from the detection of electromagnetic waves of various wavelengths, which have previously passed through a medium to be examined, especially tissue and/or vessels of a living or dead organism, and/or have been reflected by this medium;

wherein

at least for a certain percentage of the overall signal quantity, at least two measurement values are used for each generated signal, these values being so close together in time that they form a common signal; and

wherein

the signals are intended to be transmitted to a signal receiver, which can be used to support the therapy and/or treatment of an organism.

2. A signal transmitter according to claim 1, wherein, during the generation of the signals, a control device assigned to the signal transmitter takes into account the possible effects of feedback in a control circuit extending from the signal transmitter to the signal receiver and across the organism back to the signal transmitter.

3. A signal transmitter according to claim 1, wherein not only the measurement values but also parameters predefined by the signal receiver are used to generate the signals.

4. A signal transmitter according to claim 1, wherein the signal quality of the signal transmitter is checked for reliability by the signal transmitter itself on the basis of predefined and/or predefinable data, which are stored retrievably within the range of the signal transmitter and/or signal receiver.

5. A signal transmitter according to claim 1, wherein the degree of signal reliability of the signals of the signal transmitter is adjusted in accordance with parameters of the signal receiver being transmitted.

6. A signal transmitter according to claim 1, wherein not only the measurement values but also parameters transmitted by the signal receiver are determined for the signal quantity.

7. A signal transmitter according to claim 1, wherein not only the measurement values but also parameters predefined by the signal receiver are used for the signal quality of the signals.

8. A signal transmitter according to claim 1, wherein the type and/or scope of signal generation by the signal transmitter is also adjusted according to the parameters of the signal receiver being transmitted at the time in question.

9. A signal transmitter according to claim 1, wherein, during the generation of the signals, a control unit assigned to the signal transmitter takes into account the possible effects of feedback in a control circuit extending from the signal transmitter to the signal receiver and back to the signal transmitter via the organism, where the degree to which the signals of the signal transmitter can be controlled is also adjusted according to the parameters of the signal receiver being transmitted at the time in question.

10. A signal transmitter according to claim 1, wherein the degree of the feedback quality of the signals of the signal transmitter is also adjusted according to the parameters of the signal receiver being transmitted at the time in question.

11. A signal transmitter according to claim 1, wherein the physiological variable is selected from the following group:

the concentration of total hemoglobin cHb, of oxyhemoglobin HbO₂, of deoxygenated hemoglobin HbDe, of carboxyhemoglobin HbCO, of methemoglobin HbMet, of sulfhemoglobin HbSulf, of bilirubin, of bile pigments or the absolute oxygen saturation SaO₂, the relative oxygen saturation SpO₂, the oxygen supply CaO₂, or the carbon monoxide saturation SaCO.

12. A signal transmitter according to claim 1, wherein the measurement value of at least one pV is determined within 10 seconds after registration of the detected electromagnetic waves.

13. A signal transmitter according to claim 1, wherein the measurement value is determined and the signal made available for transmission via an interface within one minute after recording the detected electromagnetic waves.

14. A signal transmitter according to claim 1, wherein the measurement values of the saturation SaCO of the exposed medium correspond to the actual saturation with an accuracy of at least 2% in the range of 0-40% saturation.

15. A signal transmitter according to claim 1, wherein the measurement values of the saturation SaO₂ of the exposed medium correspond to the actual saturation with an accuracy of at least 2% in the range of 0-100% saturation.

16. A signal transmitter according to claim 1, wherein the measurement values of the saturation of methemoglobin of the exposed medium correspond to the actual saturation with an accuracy of at least 2% in the range of 0-80% saturation.

17. A signal transmitter according to claim 1, wherein the measurement values of the concentration of hemoglobin of the exposed medium correspond to the actual concentration with an accuracy of at least 2.0 g/dL.

18. A signal transmitter according to claim 1, wherein, from the time at which the electromagnetic waves pass through the tissue/vessel until the output of a value representing cHb, no more than 60 seconds elapse, where the concentration of cHb of the exposed tissue/vessel is accurate to at least 3 g/dL.

19. A signal transmitter according to claim 1, wherein, from the time at which the electromagnetic waves pass through a tissue/vessel until the output of a value representing SaCO, no more than 20 seconds elapse, where the saturation SaCO is accurate to at least 2% (in the measurement range of 0-40%).

20. A control circuit comprising a signal transmitter, which, with a signal receiving system, detects at least one physiological variable of a human being or animal and, with a signal evaluation unit, converts it into processed signals and transmits these signals to a signal receiver, where the transmitted processed signal is used in the signal receiver to influence at least one physiological parameter of the human being or animal with a direct or indirect effect on the physiological variable measured by the signal transmitter.

21. A control circuit according to claim 20, wherein the signal transmitter is a device comprising a sequence control approach is implemented in such a way that the measurement values are acquired from the detection of electromagnetic waves of various wavelengths, which have previously passed through a medium to be examined, especially tissue and/or vessels of a living or dead organism, and/or have been reflected by this medium;

wherein

at least for a certain percentage of the overall signal quantity, at least two measurement values are used for each generated signal, these values being so close together in time that they form a common signal; and

wherein

the signals are intended to be transmitted to a signal receiver, which can be used to support the therapy and/or treatment of an organism.

22. A control circuit according to claim 21, wherein the signal receiving system of the signal transmitter detects a light signal of a new wavelength after a predefined time interval.

23. A control circuit according to claim 21, wherein the predefined time interval is 1 second.

24. A control circuit according to claim 21, wherein the connection between the signal transmitter and the signal receiver is based on analog and/or digital signals, which are made available via an interface.

25. A control circuit according to claim 21, wherein the connection between the signal transmitter and the signal receiver is achieved through coupling elements for establishing a detachable mechanical and/or electronic connection between the signal transmitter and the signal receiver.

26. A control circuit according to claim 21, wherein the connection between the signal transmitter and the signal receiver can be established by a wireless connection between the signal transmitter and the signal receiver.

27. A control circuit according to claim 21, wherein the signal transmitter and/or the signal receiver has an interface by which it can be connected to additional signal transmitters and/or signal receivers such as analyzers, ECG machines, or sensor devices.

28. A control circuit according to claim 21, wherein data and/or control commands are exchanged between signal transmitters and/or signal receivers.

29. A control circuit according to claim 21, wherein the functionality of the connection between signal transmitters and signal receivers is checked, and a malfunctioning or a properly functioning connection between signal transmitters and signal receivers is communicated to the user via suitable optical and/or acoustic signal elements.

30. A control circuit according to claim 21, wherein the data connection is released through the connection between the signal transmitter and the signal receiver.

31. A control circuit according to claim 21, wherein physiological reactions of the patient which can be caused by the signal receiver are detected by the signal transmitter and sent onward for evaluation and/or remote diagnosis.

32. A control circuit according to claim 21, wherein the signal transmitter identifies different signal receivers on the basis of a code carried by each of the signal receivers.

33. A control circuit according to claim 21, wherein the signal transmitter provides different suitable presettings for each of the individual signal receivers.