ULTRASOUND ASSISTED AND X-RAY ASSISTED BIOPSY DEVICES

• US 20070282221A1
• Filed: 06/04/2007
• Published: 12/06/2007
• Est. Priority Date: 06/02/2006
• Status: Abandoned Application

• Current Assignee: U-System Inc. (General Electric Company)
• Original Assignee: U-System Inc. (General Electric Company)
• Inventors: Anderson, Tor C., Wang, Shih-Ping
• Application Number:
  US11/757,996
• Publication Number:
  US 20070282221A1
• Time in Patent Office: Days
• US Class Current: 600/564
• CPC Class Codes: A61B 10/0233 Pointed or sharp biopsy instruments
• CPC Class Codes: A61B 2090/376 using X-rays, e.g. fluoroscopy
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 90/11 with guides for needles or instruments, e.g. arcuate slides or ball joints

Abstract

Improved systems and related methods for x-ray assisted breast biopsy and ultrasound-assisted breast biopsy are described. In one preferred embodiment, for example, an apparatus for facilitating both x-ray assisted and ultrasound assisted breast biopsy is provided, comprising a biopsy table for supporting a patient in a prone position between first and second opposing ends thereof, the biopsy table having first and second openings, respectively, toward each of the first and second ends, through which the patient'"'"'s breast may project depending on the patient'"'"'s orientation on the biopsy table. The apparatus further comprises an ultrasound-assisted biopsy system positioned beneath the first opening, and an x-ray-assisted biopsy system positioned beneath the second opening. In other preferred embodiments, the ultrasound-assisted biopsy system and x-ray assisted biopsy system are mechanically interchangeable beneath a single opening. In other preferred embodiments, novel integrations between specified components of the ultrasound-assisted and x-ray-assisted biopsy systems are provided.

Claims

1-3. -3. (canceled)

4. An apparatus for facilitating image-guided breast biopsy procedures, comprising:

a biopsy table for supporting a patient in a prone position between first and second opposing ends of the biopsy table, the biopsy table having a first opening through which the prone patient'"'"'s breast may project when the patient is in a first orientation relative to said first and second ends of the biopsy table, the biopsy table having a second opening through the prone patient'"'"'s breast may project when the patient is in a second orientation relative to said first and second ends of the biopsy table;

an ultrasound-assisted biopsy system positioned beneath said first opening, the ultrasound-assisted biopsy system comprising an ultrasound probe, a first biopsy instrument insertion platform, and first and second compressive members for compressing the breast along a first plane generally perpendicular to said biopsy table;

an x-ray-assisted biopsy system positioned beneath said second opening, the x-ray-assisted biopsy system comprising an x-ray source, an x-ray detector, a second biopsy instrument insertion platform, and third and fourth compressive members for compressing the breast along a second plane generally perpendicular to said biopsy table; and

a display system coupled to each of said ultrasound-assisted biopsy system and said x-ray-assisted biopsy system for displaying medical image information generated thereby.

5. The apparatus of claim 4, said first biopsy instrument insertion platform comprising:

a first biopsy instrument for puncturing through a skin of the breast and capturing cellular tissue therein; and

a first biopsy guide supportably coupled to said first biopsy instrument for facilitating constrained linear movement of said first biopsy instrument within a plane substantially parallel to said first plane during said puncturing and capturing;

wherein said first biopsy instrument, said first biopsy guide, and said first and second compressive members are jointly rotatable around an axis generally perpendicular to said biopsy table such that said first plane is user adjustable.

6. The apparatus of claim 5, wherein said first plane is user adjustable to any of a craniocaudal (CC) direction, a mediolateral oblique (MLO) direction, and a lateral (LAT) direction.

7. The apparatus of claim 4, wherein said second orientation of the patient relative to said first and second ends of the biopsy table is substantially opposite said first orientation of the patient relative to said first and second ends of the biopsy table, and wherein said x-ray-assisted biopsy system comprises a stereotactic x-ray assisted biopsy system.

8. The apparatus of claim 4, said first compressive member comprising a first surface that contacts the breast during compression thereof and a second surface opposite said first surface, wherein said ultrasound-assisted biopsy system is configured such that said ultrasound probe is swept across said second surface to generate an ultrasound volume representative of the breast while compressed between said first and second compressive members.

9. The apparatus of claim 8, wherein said first compressive member comprises one of a vented membrane and a taut fabric sheet substantially porous to an acoustic couplant liquid or gel.

10. The apparatus of claim 9, said first biopsy instrument insertion platform comprising:

a first biopsy needle for puncturing through a skin of the breast and capturing cellular tissue therein during a biopsy procedure; and

a first biopsy guide supportably coupled to said first biopsy needle for facilitating constrained linear movement of said first biopsy instrument within a third plane during said biopsy procedure, said third plane being generally perpendicular to said first plane such that said first biopsy needle also punctures through said first compressive member during said biopsy procedure.

11. The apparatus of claim 9, said first biopsy instrument insertion platform comprising:

a first biopsy instrument for puncturing through a skin of the breast and capturing cellular tissue therein; and

a first biopsy guide supportably coupled to said first biopsy instrument for facilitating constrained linear movement of said first biopsy instrument within a plane substantially parallel to said first plane during said puncturing and capturing;

wherein said first biopsy instrument, said first biopsy guide, and said first and second compressive members are jointly rotatable around an axis generally perpendicular to said biopsy table such that said first plane is user adjustable.

12. The apparatus of claim 11, said first biopsy instrument being long and narrow in shape, said ultrasound probe being a linear ultrasound probe, wherein said linear ultrasound probe and first biopsy instrument are (i) mechanically constrained to a common plane in a connected configuration, and (ii) not mechanically constrained to a common plane in a released configuration, said connected configuration being useful for maintaining visibility of the first biopsy instrument in ultrasound images derived from the linear ultrasound probe.

13. An apparatus for facilitating image-guided breast biopsy procedures, comprising:

a biopsy table for supporting a patient in a prone position, the biopsy table having an opening through which a breast of the prone patient projects;

an ultrasound-assisted biopsy platform comprising an ultrasound probe, a first biopsy guide, a first biopsy instrument, and first and second compressive surfaces, the first and second compressive surfaces for compressing the breast along a first plane generally perpendicular to said biopsy table;

an x-ray-assisted biopsy platform comprising an x-ray source, an x-ray detector, a second biopsy guide, a second biopsy instrument, and third and fourth compressive surfaces for compressing the breast along a second plane generally perpendicular to said biopsy table; and

a display system coupled to receive medical images derived from said ultrasound probe and said x-ray detector and to display said medical image information;

wherein said ultrasound-assisted biopsy platform and said x-ray-assisted biopsy platform are movably interchangeable relative to the opening such that ultrasound assisted biopsy and x-ray-assisted biopsy of the breast can be provided at different times.

14. The apparatus of claim 13, wherein said ultrasound-assisted biopsy platform and said x-ray-assisted biopsy platform are located on separate mountings each pivotably disposed around a pivot axis, whereby said movable interchange of said ultrasound-assisted biopsy platform and said x-ray-assisted biopsy relative to said opening comprises a rotational interchange achieved by rotation of said mountings around said pivot axis.

15. The apparatus of claim 13, wherein said ultrasound-assisted biopsy platform and said x-ray-assisted biopsy platform are located on a common mounting, whereby said movable interchange of said ultrasound-assisted biopsy platform and said x-ray-assisted biopsy relative to said opening comprises a translational interchange achieved by translation of said common mountings relative to said opening.

16. The apparatus of claim 13, said first compressive member comprising a first surface that contacts the breast during compression thereof and a second surface opposite said first surface, wherein said ultrasound probe is swept across said second surface to generate an ultrasound volume representative of the breast while compressed between said first and second compressive members.

17. The apparatus of claim 16, wherein said first compressive member comprises one of a vented membrane and a taut fabric sheet substantially porous to an acoustic couplant liquid or gel.

18. The apparatus of claim 17, said first biopsy needle for puncturing through a skin of the breast and capturing cellular tissue therein during a biopsy procedure, said first biopsy guide supportably coupled to said first biopsy needle for facilitating constrained linear movement of said first biopsy instrument within a third plane during said biopsy procedure, said third plane being generally perpendicular to said first plane such that said first biopsy needle also punctures through said first compressive member during said biopsy procedure.

19. An apparatus for facilitating image-guided breast biopsy procedures, comprising:

a biopsy table for supporting a patient in a prone position, the biopsy table having a first opening through which the prone patient'"'"'s breast projects;

an ultrasound-assisted biopsy system comprising an ultrasound probe, a first biopsy guide, a first biopsy instrument, and first and second compressive members, the first and second compressive members for compressing the breast along a compression plane generally perpendicular to said biopsy table;

an x-ray-assisted biopsy platform comprising an x-ray source, an x-ray detector, a second biopsy guide, a second biopsy instrument, and third and fourth compressive members for compressing the breast along said compression plane;

a display system coupled to each of said ultrasound-assisted biopsy system and said x-ray-assisted biopsy system for displaying medical image information generated thereby;

wherein said first and third compressive members are substantially adjacent, jointly movable along a direction substantially parallel to said compression plane, and coplanar along respective surfaces thereof that contact a first side of the breast;

wherein said second and fourth compressive surfaces are substantially adjacent, jointly movable along the direction substantially parallel to said compression plane, and coplanar along respective surfaces thereof that contact a second side of the breast opposite the first side;

wherein said apparatus is configured to be slidably switched between an ultrasound-assisted biopsy mode and an x-ray assisted biopsy mode, the breast remaining substantially motionless as said first and third compressive members are slidably interchanged beneath said first opening and as said second and fourth compressive members are slidably interchanged beneath said first opening.

20. The apparatus of claim 19, said first compressive member comprising a first surface that contacts the first side of the breast during compression thereof and a second surface opposite said first surface, wherein said ultrasound-assisted biopsy system is configured such that said ultrasound probe is swept across said second surface to generate an ultrasound volume representative of the breast while compressed between said first and second compressive members in said ultrasound-assisted biopsy mode

21. The apparatus of claim 20, wherein said first compressive member comprises one of a vented membrane and a taut fabric sheet substantially porous to an acoustic couplant liquid or gel.

22. The apparatus of claim 20, said third compressive surface member forming a second opening through which said second biopsy instrument is inserted to puncture the first side of the breast during said x-ray assisted biopsy mode.

23. The apparatus of claim 22, said first biopsy instrument for puncturing through a skin of the breast and capturing cellular tissue therein during an ultrasound-assisted biopsy procedure, wherein said first biopsy guide is configured for facilitating constrained linear movement of said first biopsy instrument within a plane substantially parallel to said compression plane during said ultrasound-assisted biopsy procedure.