System and method for heightening an immune response

• US 20080147329A1
• Filed: 09/26/2007
• Published: 06/19/2008
• Est. Priority Date: 08/25/2004
• Status: Abandoned Application

• Current Assignee: Searete LLC (Intellectual Ventures LLC)
• Original Assignee: Searete LLC (Intellectual Ventures LLC)
• Inventors: Ishikawa, Muriel Y., Myhrvold, Nathan P., Jung, Edward K.Y., Sweeney, Elizabeth A., Bangera, Mahalaxmi Gita, Wood, Lowell L., Wilson, Richa
• Application Number:
  US11/904,636
• Publication Number:
  US 20080147329A1
• Time in Patent Office: Days
• US Class Current: 702/19
• CPC Class Codes: A61K 39/00 Medicinal preparations containing antigens or antibodies materials for immunoassay G01N33/53
• CPC Class Codes: C07K 16/00 Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies antibodies with enzymatic activity, e.g. abzymes C12N9/0002
• CPC Class Codes: G16B 30/00 ICT specially adapted for sequence analysis involving nucleotides or amino acids
• CPC Class Codes: G16B 30/10 Sequence alignment; Homology search
• CPC Class Codes: G16C 20/50 Molecular design, e.g. of drugs

Abstract

The present application relates, in general, to a system or method for detection or treatment. In one aspect, a method includes but is not limited to: providing one or more antigenic attributes of one or more agents associated with at least a part of an immune response in a host; and forming a set of the one or more antigenic attributes operable for modulating the at least a part of the immune response in the host.

Claims

1. A method, comprising:

providing one or more antigenic attributes of one or more agents associated with at least a part of an immune response in at least one host; and

forming a set of the one or more antigenic attributes operable for modulating the at least a part of the immune response in the at least one host.

2. The method of claim 1, wherein the at least a part of an immune response includes an actively engaged immune response.

3. The method of claim 1, wherein the one or more antigenic attributes are associated with at least one HLA type of at least one host.

4. The method of claim 1, wherein the one or more antigenic attributes are associated with at least one T lymphocyte response.

5. The method of claim 1, wherein the forming a set of the one or more antigenic attributes comprises:

forming a set including the one or more antigenic attributes displayed by the one or more agents.

6. The method of claim 1, comprising:

displaying one or more sequences corresponding to the one or more antigenic attributes of one or more agents.

7. The method of claim 1, comprising:

projecting one or more alternate courses of at least a part of the immune response in the host associated with the one or more antigenic attributes of one or more agents.

8. The method of claim 7, wherein the projecting one or more alternate courses of at least a part of the immune response in the host associated with one or more antigenic attributes of one or more agents comprises:

projecting one or more alternate courses of at least a part of an immune response specific to at least one HLA type of at least one host.

9. The method of claim 1, comprising:

projecting at least one pattern of change in the one or more antigenic attributes of one or more agents in response to at least one HLA type of at least one host.

10. The method of claim 1, wherein the forming a set of one or more antigenic attributes operable for managing at least a part of the immune response in a host comprises:

forming a set of the one or more antigenic attributes of the one or more agents amenable to a treatment.

11. A system, comprising:

a computer readable medium including, but not limited to, a computer program for use with a computer system and wherein the computer program includes a plurality of instructions including;

one or more instructions for providing one or more antigenic attributes of one or more agents associated with at least a part of an immune response in at least one host; and

one or more instructions for forming a set of the one or more antigenic attributes operable for modulating the at least a part of the immune response in the at least one host.

12. The system of claim 11, wherein the at least a part of an immune response includes an actively engaged immune response.

13. The system of claim 11, wherein the one or more antigenic attributes are associated with at least one HLA type of at least one host.

14. The system of claim 11, wherein the one or more antigenic attributes are associated with at least one T lymphocyte response.

15. The system of claim 11, wherein the one or more instructions for forming a set of the one or more antigenic attributes comprises:

one or more instructions for forming a set including the one or more antigenic attributes displayed by the one or more agents.

16. The system of claim 11, wherein the forming a set of the one or more antigenic attributes operable for modulating the at least a part of the immune response in the at least one host comprises:

forming a set including one or more antigenic attributes associated with at least one HLA type of the at least one host.

17. The system of claim 11, wherein the forming a set of the one or more antigenic attributes operable for modulating the at least a part of the immune response in the at least one host comprises:

forming a set including one or more antigenic attributes associated with at least one T lymphycyte response in the at least one host.

18. The system of claim 11, comprising:

one or more instructions for displaying one or more sequences corresponding to the one or more antigenic attributes of one or more agents.

19. The system of claim 11, comprising:

one or more instructions for projecting one or more alternate courses of at least a part of the immune response in the at least one host associated with the one or more antigenic attributes of one or more agents.

20. The system of claim 11, comprising:

one or more instructions for projecting one or more alternate courses including at least one immune response specific to at least one HLA type of at least one host.

21. The system of claim 11, comprising:

one or more instructions for projecting at least one pattern of change in one or more antigenic attributes of one or more agents in response to at least one HLA type of at least one host.

22. The system of claim 11, wherein the one or more instructions for forming a set of the one or more antigenic attributes operable for managing at least a part of the immune response in the at least one host comprises:

one or more instructions for forming a set of the one or more antigenic attributes of one or more agents amenable to a treatment.

23. The system of claim 22, wherein the treatment includes:

a treatment with at least a part of a T lymphocyte.

24. A system, comprising:

means for providing one or more antigenic attributes of one or more agents associated with at least a part of an immune response in a host; and

means for forming a set of the one or more antigenic attributes operable for modulating the at least a part of the immune response in the host.

25. A system, comprising:

circuitry configured by a computer program for providing one or more antigenic attributes of one or more agents associated with at least a part of an immune response in a host; and

circuitry configured by a computer program for forming a set of the one or more antigenic attributes operable for modulating the at least a part of the immune response in the host.