LOW POWER METHODS FOR PRESSURE WAVEFORM SIGNAL SAMPLING USING IMPLANTABLE MEDICAL DEVICES

• US 20080171941A1
• Filed: 01/11/2008
• Published: 07/17/2008
• Est. Priority Date: 01/12/2007
• Status: Abandoned Application

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Tran, Binh C., Huelskamp, Paul J., Maile, Keith R., Liao, Wangcai
• Application Number:
  US12/013,325
• Publication Number:
  US 20080171941A1
• Time in Patent Office: Days
• US Class Current: 600/484
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/7232 involving compression of the physiological signal, e.g. to extend the signal recording period
• CPC Class Codes: A61B 5/7285 for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal A61B6/5205, A61B6/541, A61B8/5207, A61B8/543 take precedence

Abstract

Systems and methods for reducing power consumption in implantable medical devices (IMDs) in which an IMD implantable in an artery monitors blood pressure. A master device monitors a physiological signal, such as respiratory cycle, and instructs the IMD to take blood pressure measurements over a sampling interval, the duration of which is determined by the master device based on the monitored physiological signal. The master device may determine an end-expiration point of the respiratory cycle and send synchronization information to the IMD to further shorten the sampling interval by coinciding the sampling interval with the end expiration point of the respiratory cycle. The IMD may further conserve power by including processing abilities to collect and/or transmit only a subset of data representing the blood pressure signal, for example, systolic, diastolic, and/or mean blood pressure signal values. The blood pressure readings, once taken, may be transferred to the master device.

Claims

1. A method for operating an implantable medical device (IMD), the method comprising:

receiving a physiological signal of a patient;

determining a respiration rate of the patient based on the received physiological signal;

determining with a processor located within the IMD a sampling interval based on the determined respiration rate of the patient;

determining a sampling mode based upon system conditions and external inputs, wherein the sampling mode includes one or more operating parameters; and

recording blood pressure measurements of the patient over the sampling interval according to the one or more operating parameters included in the sampling mode.

2. The method of claim 1, further comprises discriminating between local extrema and global extrema of the blood pressure measurement, wherein discriminating comprises:

setting a discriminator time interval based upon the received physiological signal;

detecting a possible extrema while taking blood pressure measurements during the sampling interval; and

recording the possible extrema if a new extrema is not detected during the discriminator time interval after the detection of the possible extrema.

3. The method of claim 1, wherein the one or more sampling mode parameters are selected from the group consisting of sample rate, maximum sample rate, minimum sample rate, data compression rate, maximum data compression rate, minimum data compression rate, data transfer method, generation of statistical information, sampling interval, maximum sampling interval, minimum sampling interval, choice of physiological signals, use of triggering signal, synchronization mode, accuracy level and measurement frequency.

4. The method of claim 1, wherein the system conditions for determining the sampling mode include remaining power of the IMD and availability of a synchronization signal.

5. The method of claim 1, wherein the external inputs are sent from a second IMD and include one or more of a requested accuracy level, data transfer method, and measurement frequency.

6. The method of claim 1, further comprising:

predicting when an end-expiration ventilation of the patient will occur based on the received physiological signal; and

synchronizing a start of the sampling interval so that the predicted end-expiration ventilation will occur during the sampling interval.

7. An implantable medical device system with reduced power consumption, the system comprising:

a master device configured to receive a first physiological signal of a patient, to determine a sampling interval duration based on the first physiological signal, and to send an instruction containing the sampling interval duration; and

a slave implantable medical device configured to receive the instruction containing the sampling interval duration, to sense a second physiological signal, and to record one or more data points from the second physiological signal over the sampling interval duration.

8. The implantable medical device system of claim 7, wherein the slave implantable medical device is further configured to send the one or more recorded data points to the master device.

9. The implantable medical device system of claim 7, wherein the first physiological signal is a respiration cycle signal, and wherein the second physiological signal is a blood pressure signal.

10. The implantable medical device system of claim 9, wherein the master device is further configured to determine an end expiration point of the respiration cycle signal, wherein the sampling interval duration is smaller than a duration of one full period of the respiration cycle signal, and wherein the instruction further contains synchronization information useable by the slave implantable medical device to coincide the sampling interval duration with the end expiration point.

11. The implantable medical device system of claim 9, wherein the slave implantable medical device is further configured to calculate a statistic of the one or more data points, the statistic selected from the group consisting of:

a minimum, a maximum, and an average.

12. The implantable medical device system of claim 11, wherein the master device is further configured to command the slave implantable medical device to send the statistic to the master device.

13. The implantable medical device system of claim 9, wherein the slave implantable medical device is further configured to track peaks and valleys of the blood pressure signal and to record the one or more data points from the blood pressure signal substantially corresponding to peaks or valleys of the blood pressure signal.

14. The implantable medical device system of claim 13, wherein the slave implantable medical device is further configured to discriminate between local extrema and global extrema within the blood pressure signal.

15. The implantable medical device system of claim 9, wherein the respiration cycle signal is a minute ventilation signal.

16. The implantable medical device system of claim 7, wherein the master device is a master implantable medical device.

17. The implantable medical device system of claim 16, wherein the master implantable medical device is a pulse generator.

18. The implantable medical device system of claim 7, wherein the slave implantable medical device comprises:

a battery capable of generating a status signal indicating a current level of charge; and

a sampling mode module to use the status signal to determine an appropriate sampling mode.

19. The implantable medical device system of claim 7, wherein the slave implantable medical device comprises:

a memory to store the one or more data points;

a sampling mode module to determine a sampling mode of a pressure sensor module of the slave implantable medical device, the sampling mode including sample rate, data compression rate, and measurement frequency; and

a communications module to retrieve the one or more data points from the memory and transmit the one or more data points to the master device.

20. The implantable medical device system of claim 9, wherein the instruction includes a timing signal generated by:

determining the duration of the sampling interval so that a desired data point of the blood pressure signal will lie within the sampling interval; and

centering the sampling interval around the desired data point.

21. A method comprising:

monitoring with an implanted sensor module a physiological signal to determine a respiration rate of a patient;

determining with a processor a sampling interval based on the respiration rate of the patient; and

recording blood pressure measurements during the sampling interval.

22. The method of claim 21, further comprising:

predicting when a specific ventilation state will occur based on a received physiological signal; and

synchronizing a start of the sampling interval so that the ventilation state will occur as predicted during the sampling interval.

23. The method of claim 21, further comprising:

receiving a control signal from a master implantable medical device, wherein the control signal includes information about the number of times per day the blood pressure measurements should occur and whether all or a subset of the blood pressure measurements should be transmitted to the master IMD; and

transmitting blood pressure measurements, as indicated by the control signal, to the master IMD.

24. The method of claim 21, further comprising receiving a signal indicating a desired sampling mode, wherein the desired sampling mode includes information about sampling rate, number of measurements per day, and desired compression scheme.