Dose Setting Mechanism for an Injection Device

• US 20080208142A1
• Filed: 02/24/2006
• Published: 08/28/2008
• Est. Priority Date: 02/28/2005
• Status: Abandoned Application

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Moller, Claus Schmidt
• Application Number:
  US11/816,917
• Publication Number:
  US 20080208142A1
• Time in Patent Office: Days
• US Class Current: 604/208
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31535 Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
• CPC Class Codes: A61M 5/31538 Permanent blocking, e.g. by medical personnel
• CPC Class Codes: A61M 5/31541 Means preventing setting of a dose beyond the amount remaining in the cartridge
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member
• CPC Class Codes: A61M 5/31575 using scaling up or down transmissions, e.g. gearbox
• CPC Class Codes: A61M 5/31583 based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
• CPC Class Codes: A61M 5/50 having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile retractable needles or needle protectors with means for preventing re-use A61M5/321

Abstract

A dose setting mechanism for an injection device, e.g. for repetitive self-injection of e.g. insulin or growth hormone. Has a dose setting member, a driving element for causing a set dose to be injected, and a locking member being connected to the driving element. The position of the locking member is indicative of the remaining amount of liquid in a cartridge. When the amount is below a critical lower value, the locking member assumes a locking position where it prevents the dose setting member from being operated to set a dose.

Ensures that a dose can only be set if the remaining amount of liquid in the cartridge is sufficient to ensure proper mixing of the contents of the liquid. At the same time ensures optimal usage of the available liquid. Particularly suitable for injection devices for long acting or mix insulin.

Claims

1. A dose setting mechanism for an injection device, the dose setting mechanism comprising:

a dose setting member being operable by a user to set a desired dose,

a driving element being adapted to drive a piston rod, thereby causing a set dose to be injected by the injection device,

a locking member being operatively connected to the driving element in such a way that movement of the driving element during injection of a set dose causes a movement of the locking member, a position of the locking member thereby being indicative of a remaining amount of liquid in a cartridge of the injection device, the locking member further being adapted to assume a locking position when the remaining amount of liquid is below a predefined critical lower value,

wherein the locking member, when in the locking position, prevents the dose setting member from being operated to set a dose, and wherein the dose setting mechanism may be operated to set and inject a dose when the locking member is not in the locking position, even if injection of the set dose results in the remaining amount of liquid falling below the predefined critical lower value.

2. The dose setting mechanism according to claim 1, wherein the locking member is adapted to move along a longitudinal axis of the injection device during injection of a set dose.

3. The dose setting mechanism according to claim 1, wherein the locking member is further operatively connected to the dose setting member in such a way that movement of the dose setting member during dose setting causes a movement of the locking member.

4. The dose setting mechanism according to claim 3, wherein the locking member is adapted to perform a substantially translational movement along a longitudinal axis of the injection device during injection of a set dose, and adapted to perform a rotational movement about said longitudinal axis during setting of a dose.

5. The dose setting mechanism according to claim 4, wherein the locking member comprises a set of teeth being adapted to engage one or more mating teeth in such a way that rotational movement of the locking member is prevented, the engagement of said teeth thereby defining the locking position of the locking member.

6. The dose setting mechanism according to claim 1, wherein the locking position of the locking member is a position in which the locking member prevents a decoupling of the dose setting member and/or the driving element from a housing of the injection device.

7. An injection device comprising a dose setting mechanism according to claim 1.

8. The dose setting mechanism according to claim 2, wherein the locking member is further operatively connected to the dose setting member in such a way that movement of the dose setting member during dose setting causes a movement of the locking member.

9. The dose setting mechanism according to claim 8, wherein the locking member is adapted to perform a substantially translational movement along a longitudinal axis of the injection device during injection of a set dose, and adapted to perform a rotational movement about said longitudinal axis during setting of a dose.

10. The dose setting mechanism according to claim 9, wherein the locking member comprises a set of teeth being adapted to engage one or more mating teeth in such a way that rotational movement of the locking member is prevented, the engagement of said teeth thereby defining the locking position of the locking member.

11. An injection device comprising a dose setting mechanism according to claim 2.

12. An injection device comprising a dose setting mechanism according to claim 3.

13. An injection device comprising a dose setting mechanism according to claim 4.

14. An injection device comprising a dose setting mechanism according to claim 5.

15. An injection device comprising a dose setting mechanism according to claim 6.

16. An injection device comprising a dose setting mechanism according to claim 8.

17. An injection device comprising a dose setting mechanism according to claim 9.

18. An injection device comprising a dose setting mechanism according to claim 10.